Results 201 to 210 of about 8,067,926 (304)

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Caregiving ability assessment tools for family caregivers of disabled older adults: a scoping review. [PDF]

Front Public Health
Fu J, Feng Y, Si X, Wang C, Zhang L, Zhang Y.   +5 more
europepmc   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Nutritional interventions for late-life depression: evidence, mechanisms, and clinical assessment tools. [PDF]

Front Nutr
Li ZK, Gao Y, Li HN, Peng YX, Qiao JJ, Liu S, Yan X.   +6 more
europepmc   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Risk Assessment Tools for Mass Gatherings: a Narrative Review. [PDF]

J Epidemiol Glob Health
Shabani E, Ghasempour A, Nazari F, Fini HN.   +3 more
europepmc   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Research progress of symptom clusters and assessment tools in patients with chronic kidney disease

Huli yanjiu, 2023
TIAN Xueqi, KONG Yan, ZONG Kejing, CHANG Lei, LIU Yanli, ZHANG Jing   +5 more
doaj  

Bedside screening and assessment tools for sarcopenia, dysphagia and malnutrition in older adults with dementia: a scoping review

Adeniji T, Kolawole FO, Okemuo A, Fawole HO, Akinrolie O, McCartney A, Roberts S, Adjei-Nicol S, Rajkumar AP, Stephensen D.   +9 more
europepmc   +1 more source

Malnutrition Is Common in Cyclic Vomiting Syndrome: A Prospective Study Using Validated Nutritional Assessment Tools. [PDF]

Dig Dis Sci
Venkatesan T, Goday PS, Arumugam S, Gofar K, Vyas M, Petrova A, Raul JC, Ayyan M, Srivastava S, Heitman K, Madril P, Goheen K, Roberts KM.   +12 more
europepmc   +1 more source