Results 31 to 40 of about 45,773 (257)

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho   +7 more
wiley   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

EURASIAN RESERVE SYSTEM: CONCERNING MECHANISM OF FINANCING SOCIALLY IMPORTANT INFRASTRUCTURAL ECOLOGICAL PROJECTS AND PROGRAMS

open access: yesВестник Российского экономического университета имени Г. В. Плеханова, 2018
The lake Baikal, as an object of the global nature heritage is facing an ecological disaster of the national scale. This is one of the most important conclusions drawn by the Baikal International Ecological Water Forum while discussing problems of ...
Vyacheslav I. Karpunin   +1 more
doaj   +1 more source

Algorithmic portfolio tilting to harvest higher moment gains

open access: yesHeliyon, 2020
Many financial portfolios are not mean-variance-skewness-kurtosis efficient. We recommend tilting these portfolios in a direction that increases their estimated mean and third central moment and decreases their variance and fourth central moment.
Kris Boudt   +3 more
doaj   +1 more source

Urban Heat Risk: Protocols for Mapping and Implications for Colombo, Sri Lanka

open access: yesAtmosphere, 2023
Global and urban-induced local warming lead to increasing heat risk in cities. The rapid increase in urban population, weak infrastructure, poverty, as well as an ageing population, make the risk more acute in developing cities. However, heat risk is not
Rohinton Emmanuel   +6 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Overtone Window. Practical Application of the Theory of Social and Economic Mechanisms

open access: yesВестник Российского экономического университета имени Г. В. Плеханова, 2023
The article elaborates the conceptual material published earlier in the journal (Russia has Spread its Wings. Phenomenology of Developing the Global System Contradiction of Our Era// Vestnik of the Russian Plekhanov University of Economics. – 2022. – Vol.
V. I. Karpunin, T. S. Novashina
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

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