Results 41 to 50 of about 964,304 (286)

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

Impact of expenses on total return of actively managed equity funds

open access: yesИнтеллект. Инновации. Инвестиции, 2019
Investment funds play a leading role as a main instrument savings in economical systems of the developed countries. This appears in the fact that share of investment funds exposing to stocks and bonds is considerable in household savings; net asset value
A.O. Valukhov
doaj   +1 more source

Asset liability management using stochastic programming [PDF]

open access: yes, 2003
This chapter sets out to explain an important financial planning model called asset liability management (ALM); in particular, it discusses why in practice, optimum planning models are used.
Kyriakis, T, Mitra, G, Pirbhai, M
core  

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Raising the bar on the foreign portfolio to 25 per cent: Strategic implications for South African investors

open access: yesSouth African Journal of Economic and Management Sciences, 2015
Regulation 28 of the Pension Funds Act now permits an increased allocation of 25 per cent to foreign investments. The regulation previously only permitted a 20 per cent allocation.
David John Bradfield, Brian Munro
doaj   +1 more source

Vadasz Number Effects on Convection in a Vertical Rotating Porous Layer, Placed Far from Axis of Rotation, and Subjected to Internal Heat Generation and Centrifugal Jitter

open access: yesPhysics, 2021
The flow and heat transfer in a rotating vertical porous layer, placed far from the axis of rotation, and subjected to internal heat generation and centrifugal jitter, is considered.
Saneshan Govender
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Universal pattern in fermion mass ratios and implications for flavor models

open access: yesEuropean Physical Journal C: Particles and Fields
We show that a single analytic expression using only the labels that distinguish Standard Model mass eigenstates—the ordering index $$d\in \{1,2,3\}$$ d ∈ { 1 , 2 , 3 } and electric charge $$q$$ q —fits all fermion mass ratios with high precision and ...
Samir Varma
doaj   +1 more source

Urban microclimate in temperate climates: a summary for practitioners

open access: yesBuildings & Cities, 2021
A summary is presented of current knowledge and key considerations in urban climate mitigation that have a bearing on planning practice in temperate climates.
Rohinton Emmanuel
doaj   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha   +4 more
wiley   +1 more source

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