CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Mission Drift or Strategic Expansion? Non-Core Lending, Risk, and Capital in US Credit Unions
This study investigates credit unions’ expansion into non-core lending and its association with risk and financial resilience. Using US credit union call report data from 1994 to 2024, we measure the share of purchased loans, lease receivables, and loans
Changjie Hu, Zhu Chen, Ting Cao
doaj +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Financial Stability, Prudential Regulation, and Bank Performance: Panel Evidence from Nigeria
Purpose This study examines the effect of bank-specific financial soundness indicators on the performance of listed Deposit Money Banks (DMBs) in Nigeria.
Emmanuel Imuede OYASOR oysar
doaj +1 more source
Bank Asset Quality in Emerging Markets: Determinants and Spillovers
This paper assesses the vulnerability of emerging markets and their banks to aggregate shocks. We find significant links between banks' asset quality, credit and macroeconomic aggregates. Lower economic growth, an exchange rate depreciation, weaker terms of trade and a fall in debt-creating capital inflows reduce credit growth while loan quality ...
Reinout De Bock, Alexander Demyanets
openaire +3 more sources
The Asset Quality Review and Capital Needs: Why re-capitalise banks with public money? CEPS Policy Brief No. 311, 19 December 2013 [PDF]
It is generally assumed that any capital needs discovered by the Asset Quality Review the ECB is scheduled to finish by the end of 2014 should be filled by public funding (= fiscal backstop). This assumption is wrong, however.
Gros, Daniel.
core
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Accounting Asset Informativeness Based on Intrinsic and Optional Factors and Investors' Beliefs: Investigating the Effects of Accounting Earnings Quality [PDF]
Assets are crucial for companies' current and future decisions, significantly influencing investors' perceptions. This study investigates the relationship between accounting asset informativeness and investors' beliefs, with a focus on the impact of ...
Zahra Heidary Sureshjani +2 more
doaj +1 more source
Determinants of Bank Asset Quality and Profitability - An Empirical Assessment [PDF]
Abstract Determinants of default risk of banks in emerging economies have so far received inadequate attention in the literature. Using panel data techniques, this paper seeks to study the determinants bank asset quality and profitability using robust data sets for the period from 1997–2009.
openaire +1 more source
Asset Management Best Practice Guidelines / Version 1.0
With the professionalisation and globalisation of solar investors and investment portfolios, service quality expectations rising steadily, putting increasing requirements on Asset Managers, who are expected to continuously improve the return on ...
Christophe Campistron +30 more
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