Effect of terahertz irradiation on DNA damage repair in living cells
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno +3 more
wiley +1 more source
Exploring Assistive Technology for Assistance Dog Owners in Emergency Situations [PDF]
Many vulnerable individuals own an assistance dog. Previous work has shown that a domestic alarm, Ringsel, allows assistance dogs to "call for help" via a canine interface that they interact with by pulling a detachment off with their mouths.
Guest, Claire +9 more
core +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Temporal consistency of behavior trait measurements in guide dogs
Guide dog organizations have strict criteria to breed, raise, and select dogs to assist people with visual impairments. In collaboration with Dr. James Serpell, several guide dog training organizations developed a scoring tool called the Behavior ...
Emma K. Hilby +7 more
doaj +1 more source
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
Exploring the Experiences of Volunteer Assistance Dog Puppy Raisers from the Same Program at Two Australian University Campuses. [PDF]
Morwood S +4 more
europepmc +1 more source
Minnesota 4-H dog show guide. [PDF]
University of Minnesota, Agricultural Extension Service; 4-H Dog Program Development Committee. (1983). Minnesota 4-H dog show guide..
4-H Dog Program Development Committee +1 more
core
Application of an Adapted Behaviour Change Wheel to Assistance Dog Puppy Raising: A Proposed Raiser-Centred Support Program. [PDF]
Mai DL, Howell T, Benton P, Bennett PC.
europepmc +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source

