Results 101 to 110 of about 1,666,748 (315)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Roadmapping interoperability requirements in assisted living

open access: yesInternational Journal of Integrated Care, 2013
Graham Worsley, Eaglesham John
doaj   +3 more sources

Effects of vaginal vs oral progesterone supplementation before embryo transfer on live birth rates and levels: a randomized trial

open access: yesReproduction and Fertility
The increase in frozen embryo transfers (FETs) is a consequence of advances in embryo vitrification and the implementation of genetic screening of embryos.
Gorka Barrenetxea   +8 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Plate Heat Exchanger Optimization Using Different Approximation Assisted Multiobjective Optimization Techniques

open access: yes, 2012
This paper presents a comparison between different multiobjective optimization approaches that can be used to optimize the design of thermal equipment. Plate heat exchanger is taken as case study to apply different optimization techniques.
Aute, Vikrant   +3 more
core  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Reduced-Complexity Near-Optimum Genetic Algorithm Assisted Multiuser Detection for Synchronous Multicarrier CDMA

open access: yes, 2004
In this contribution, a Genetic Algorithm (GA) assisted Multiuser Detector (MUD) designed for MC-CDMA is investigated in the context of frequency selective Rayleigh fading channels.
Wei, H., Hanzo, L.
core  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Effectiveness of Computer Assisted Laboratory Instructions:Learning Outcomes Analysis

open access: yes, 2007
This study investigates the impact of computer assisted instructions on learning effectiveness in computer aided design and manufacturing modules which are integral to mechanical engineering related courses.
Abdulrasool, Salah Mahdi   +4 more
core  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

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