Results 111 to 120 of about 5,460,516 (329)
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh+8 more
wiley +1 more source
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song+11 more
wiley +1 more source
Progress on Symmetry Breaking and Generational Mixing in Topcolor-Assisted Technicolor [PDF]
Topcolor-assisted technicolor provides a dynamical explanation for electroweak and flavor symmetry breaking and for the large mass of the top quark without unnatural fine tuning.
Lane, Kenneth
core +1 more source
Plasmon assisted transport through disordered array of quantum wires
Phononless plasmon assisted thermally activated transport through a long disordered array of finite length quantum wires is investigated analytically. Generically strong electron plasmon interaction in quantum wires results in a qualitative change of the
A. L Chudnovskiy+6 more
core +1 more source
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton+17 more
wiley +1 more source
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
The Positive Assistance of Assisted Reproductive Technology
Seizure Control in Women With Epilepsy Undergoing Assisted Reproductive Technology Abdulrazaq AA, Ainsworth AJ, Britton JW, Shenoy CC, Babayev SN, Cascino GD, Smith KM. Epilepsia . 2023;64(10):e207-e213.
openaire +2 more sources
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach+8 more
wiley +1 more source
Deborah A. Newton, Amy G. Dell
openaire +6 more sources
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche+8 more
wiley +1 more source