Results 61 to 70 of about 1,925,600 (298)

Control Design for a Power-Assisted Mobile Trainer: Applied to Clinical Stroke Rehabilitation

open access: yesMachines
This paper presents control design and implementation for a power-assisted mobile trainer that employs neuro-developmental treatment (NDT) principles.
Fu-Cheng Wang   +6 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Establishing the market for assisted living solutions

open access: yes, 2022
3 S.Comprehensive assisted living solutions require interdisciplinary contributions, during development as well as during operation. What can be done, so that the prerequisites for a real market for comprehensive assisted living solutions are fulfilled ...
Kleinberger, Thomas
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

The Use of an Air-Inflated Pillow for Assisted Recovery After General Anaesthesia in Horses: A Preliminary Study

open access: yesAnimals
Different assisted recovery techniques have been developed to enhance the safety and quality of equine recoveries. This case series evaluates the recovery of horses using an air-inflated pillow (Equi-lift®).
Zoë Vandaele   +3 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Assessment of Natural User Interactions for Robot-Assisted Interventions

open access: yesCurrent Directions in Biomedical Engineering, 2018
Robotic assistance in clinical interventions provides high precision and performance. However, the acceptance of such systems is still very low. The idea of collaborative robotics promises practical solutions for this problem.
Berger Johann   +5 more
doaj   +1 more source

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