Results 61 to 70 of about 200,361 (330)
Why Using Religious Arguments in the Euthanasia Discussion is Problematic
Revista Latinoamericana de Bioética, 2021 In discussions about assisted dying (euthanasia, assisted suicide), those who argue ‘against’ legalisation often reason from a religious angle, whereas those ‘in favour’ adopt a secular stance.
Theodoor A. Boer
doaj +1 more source
Physician Assisted Dying: A Turning Point? [PDF]
, 2016 Physician Assisted Dying (PAD) has been lawful in some countries since the 1940s and in the United States since 1997. There is a body of social and scientific research that has focused on whether the practice has been misused and whether gaps exist in ...
Gostin, Lawrence O., Roberts, Anna E.
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Twitter and assisted dying: using social media analysis software to evaluate the conversation around assisted dying in terms of guidelines on responsible reporting of suicide [PDF]
, 2017 News reports of assisted dying can trigger individuals to end their own lives. Social media is unaccountable to guidelines on reporting suicides. Radian6 social media analysis software was used to explore whether Twitter messages breached guidelines on ...
Cooper, Max, Hodson, Nathan
core
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Involvement of palliative care in euthanasia practice in a context of legalized euthanasia : a population-based mortality follow-back study [PDF]
, 2017 Background: In the international debate about assisted dying, it is commonly stated that euthanasia is incompatible with palliative care. In Belgium, where euthanasia was legalized in 2002, the Federation for Palliative Care Flanders has endorsed the ...
Chambaere, Kenneth +3 more
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
The Constitutional Right to Die: Ethical Considerations [PDF]
, 1997 In this commentary, the author first looks at some ethical reasoning supporting physician-assisted dying. Second, he examines some of the lines that have been drawn between withdrawing and withholding life-sustaining treatment on the one hand, and ...
Gostin, Lawrence O.
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Canadian Journal of Bioethics, 2018 The recent change in Canadian law to allow access to medical assistance in dying restricts eligibility, among its other criteria, to those for whom “natural death has become reasonably foreseeable.” A recent review of certain aspects of the law examined
Kevin Reel
doaj +1 more source