Results 81 to 90 of about 919,210 (272)

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Declarations on euthanasia and assisted dying [PDF]

open access: yes, 2017
Declarations on end of life issues are advocacy interventions that seek to influence policy, raise awareness and call others to action. Despite increasing prominence, they have attracted little attention from researchers.
Clark, David   +7 more
core   +1 more source

A Role for Judges in Assisted Dying [PDF]

open access: yesJournal of Medical Ethics and History of Medicine, 2009
Medically provoked death, whether euthanasia or assisted suicide, is a common issue for discussion in various forums, participants coming from widely differing fields of knowledge, among who are, of course, doctors. Substantial legal differences exist in
Ana Castelló   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Attitudes toward Medically Assisted Dying Among the General Public in Slovenia

open access: yes
The aim of this study was to explore public attitudes toward medically assisted dying, focusing on the role of socio-demographic factors, mental health conditions, and personal experiences.
Rojs, L   +5 more
core   +1 more source

How (not) to define ‘assisted dying’ [PDF]

open access: yes
In the last twenty years ‘assisted dying’ (and/or its variants ‘assisted death’, ‘assistance in dying’, ‘aid in dying’) has become increasingly prevalent as a term to denote the intentional ending of the life of a patient by or with the assistance of a ...
Jones, David Albert
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Assisted dying is not the same as withdrawing or withholding life sustaining treatment – Letter on Costello and Fazzini

open access: yes
Dear Editor, We read with interest, the publication by Costello and Fazzini,1 which reports a scoping review examining the attitudes and practices of intensive care unit (ICU) clinicians in relation to assisted dying. Assisted dying emphasises choice and
Hewitt, Jayne   +2 more
core   +1 more source

Catholic views on assisted dying

open access: yes, 2023
RESEARCH QUESTIONS • How do the religious views of elderly Catholic members of a church community in Auckland influence their thinking about assisted dying?
Mario, Mary Petera
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

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