Results 61 to 70 of about 862,585 (258)

Life, death, and ethics: medical and dental students’ attitudes on assisted dying in Austria

open access: yesBMC Health Services Research
Background The Sterbeverfügungsgesetz (StVfG) Austria’s law on assisted dying, came into force on January 1, 2022. Since then, only limited research has examined the attitudes of medical and dental students in Austria toward assisted dying.
Carmen Trost   +4 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

The Compassionate State? ‘Voluntary Assisted Dying’, Neoliberalism, and a Virtue Without an Anchor [PDF]

open access: yes, 2023
This article does not focus on the ethical issues surrounding the newly legal interventions that the Act legalises, referred to by the Cambridge Textbook of Bioethics as ‘physician assisted suicide’ and ‘euthanasia’.4 Commentaries that analyse the ethics
Fleming, D
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Self-Administration or Practitioner Administration? The Scope of Future German Assisted Dying Legislation

open access: yes, 2023
In 2020, the German Federal Constitutional Court declared unconstitutional and void a 2015 criminal law penalising suicide assistance in a recurring fashion and called into existence a right to a self-determined death, including the use of suicide ...
Braun, Kerstin
core   +1 more source

A qualitative study of experiences of institutional objection to medical assistance in dying in Canada: ongoing challenges and catalysts for change

open access: yesBMC Medical Ethics, 2023
Background In June 2016, Canada legalized medical assistance in dying (MAiD). From the outset, some healthcare institutions (including faith-based and non-faith-based hospitals, hospices, and residential aged care facilities) have refused to allow ...
Eliana Close   +4 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Who joins a UK right to die society and why? : a study of members of Friends at the End (FATE) [PDF]

open access: yes, 2012
PhDThe thesis presents quantitative and qualitative thematic analyses of a postal survey and interview study of members of Friends at the End (FATE), a Glasgow-based right to die society.
Judd, Marion Buchanan
core   +4 more sources

Medical Assistance in Dying: Challenges of Monitoring the Canadian Program

open access: yesCanadian Journal of Bioethics, 2020
The Canadian medical assistance in dying (MAID) program, based on an ambitious piece of legislation and detailed regulations, has failed to provide Canadians with sufficient publicly accessible evidence to show that it is operating as mandated by the ...
Jaro Kotalik
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

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