Results 131 to 140 of about 1,448,946 (300)

Predictive potential of combined secretomics and image-based morphometry as a non-invasive method for selecting implanting embryos

Reproductive Biology and Endocrinology
Background Non-invasive selection of human embryos for in vitro fertilization purposes is still a major challenge to pursue. Therefore, this study aims to identify non-invasive morphometric and secretomic parameters that reliably select the embryos with ...
Andrea Palomar, Roberto Yagüe-Serrano, Juan Vicente Martínez-Sanchis, Ignacio Iniesta, Alicia Quiñonero, Pedro José Fernández-Colom, Ana Monzó, José María Rubio, Inmaculada Molina, Francisco Domínguez   +9 more
doaj   +1 more source

Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova, Jan Smeitink, Herma Renkema, Rosabeth White, Frankie Barton, Rachel Lyon, Jane Newman, Aye Moe, Yi Shiau Ng, Grainne Siobhan Gorman   +9 more
wiley   +1 more source

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin, Tianyuan Yang, Minglei Liu, Haiyang Luo, Jing Yuan, Ke Zhang, Xinsheng Han, Jing Yang, Yuming Xu   +8 more
wiley   +1 more source

Overview Chapter 3: Birth regulation in Europe [PDF]

Early in the 21st century modern contraception -- primarily hormonal methods, advanced IUDs, sterilization and condoms -- has become the main instrument of birth regulation in Northern and Western Europe and gaining ground in Southern Europe and the ...
Tomas Frejka
core  

Laser-assisted hatching is associated with reduced re-expansion of vitrified-thawed blastocysts and has no significant effect on embryo implantation

Journal of Ovarian Research
Background Studies have shown that vitrified-thawed blastocyst re-expansion capacity is a good predictor of implantation. However, whether assisted hatching (AH) influences re-expansion is currently unstudied.
Shutian Jiang, Xueyi Jiang, Yan Mi, Xue Sun, Qifeng Lyu, Wenzhi Li   +5 more
doaj   +1 more source

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias, Federica Avantaggiato, Gianni Pezzoli, Andrea Canessa   +3 more
wiley   +1 more source

Gravity‐Dependent Modulation of Downbeat Nystagmus: Insights From Velocity‐Storage Dysfunction

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Downbeat nystagmus varies with head position, a phenomenon termed gravity‐dependent modulation. We aimed to clarify its mechanism using a velocity‐storage model. Methods In 10 patients with downbeat nystagmus due to cerebellar disorders, we recorded eye movements at different pitch‐ and roll‐axis head positions.
Ji‐Hyung Park, Eun‐Hyuk Choi, Jorge Otero‐Millan, David S. Zee, Jeong‐Yoon Choi, Ji‐Soo Kim   +5 more
wiley   +1 more source

Finland as a Late Regulator of Assisted Reproduction : A Permissive Policy under Debate

, 2016
The chapter discusses how Finland, a country that sits well within the framework of modern western semi-secular welfare democracies, is counted among the more permissive countries of Europe when it comes to legislation and practices of assisted ...
Eriksson, Lise,
core  

Cycle Control and assisted Reproduction in Cats

, 2011
The cat has been considered an important model to study 36 human pathologies and is also a valuable comparative model for assisted reproduction in endangered non-domestic felids.
CUNTO, MARCO, ZAMBELLI, DANIELE, MERLO, BARBARA   +2 more
core   +1 more source

Building a Framework for Sexual and Reproductive Health Care in the Rheumatology Context: Content and Approaches

Arthritis Care &Research, EarlyView.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source