Results 111 to 120 of about 1,514,263 (301)

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Risk factors and treatment strategies for live birth in women with high BMI undergoing ART

BMC Medicine
Background Women with a high BMI represent a growing and challenging population in assisted reproductive technology, as known impairments to treatment outcomes.
Yunhan Nie, Yuting Huang, Zhe Kuang, Mingru Yin, Xi Shen, Yali Liu, Hongyuan Gao, Hui Long, Li Wang   +8 more
doaj   +1 more source

Intramuscular injection of human chorionic gonadotropin as luteal phase support in artificial cycle frozen-thawed embryo transfer does not improve clinical outcomes: a parallel, open-label randomized trial

Frontiers in Endocrinology
BackgroundHuman chorionic gonadotropin (hCG) as one of the first signals secreted by the embryo to the mother may have a direct effect on the endometrium at implantation.
Xiaofang Li, Yu Huang, Yu Huang, Zan Shi, Juanzi Shi, Na Li   +5 more
doaj   +1 more source

Finland as a Late Regulator of Assisted Reproduction : A Permissive Policy under Debate

, 2016
The chapter discusses how Finland, a country that sits well within the framework of modern western semi-secular welfare democracies, is counted among the more permissive countries of Europe when it comes to legislation and practices of assisted ...
Eriksson, Lise,
core  

Seasonal variability in the fertilization rate of women undergoing assisted reproduction treatments

, 2012
The objective of this study was to evaluate whether seasonality affects human-assisted reproduction treatment outcomes. For this, 1932 patients undergoing intracytoplasmic sperm injection (ICSI) were assigned to a season group according to the day of ...
Savio Figueira, Rita de Cassia, De Almeida Ferreira Braga, Daniela Paes, Borges, Edson [UNESP], Iaconelli, Assumpto, Setti, Amanda, Borges, Edson   +5 more
core   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Intrafollicular soluble receptor for advanced glycation end products (sRAGE) and embryo quality in assisted reproduction

, 2013
The developmental potential of human embryos has important implications in assisted reproduction and depends, among other factors, on oocyte competency.
Bonetti, Tatiana C. S. [UNIFESP], Braga, Daniela P. A. F., Iaconelli, Assumpto, Kleine, Joao P. [UNIFESP], Borges, Edson, Silva, Ismael D. C. G. [UNIFESP]   +5 more
core   +1 more source

Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling

FEBS Open Bio, EarlyView.
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt, Annika Winbo, Jenny Malmström   +2 more
wiley   +1 more source

Development and validation of a clinical prediction model for poor ovarian response in assisted reproductive technology

Frontiers in Endocrinology
ObjectiveThe aim of this study was to develop and validate a predictive model for poor ovarian response (POR) in patients undergoing Assisted Reproductive Technology (ART).MethodsThis retrospective cohort study included 1,789 patients who underwent IVF ...
Xin Xin, Xin Xin, Xin Xin, Zhaoxia Cheng, Zhaoxia Cheng, Zhaoxia Cheng, Ting Hu, Ting Hu, Ting Hu, Yi Guo, Yi Guo, Yi Guo, Nan Li, Nan Li, Nan Li, Junbo Zhao, Junbo Zhao, Junbo Zhao, Shuaishuai Guo, Shuaishuai Guo, Shuaishuai Guo   +20 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source