Results 141 to 150 of about 51,339 (307)

Freezing the Biological Clock: A Viable Fertility Preservation Option for Young Singaporean Women?

, 2013
In March 2012, an article in The Straits Times entitled ‘Freezing eggs could reverse falling birth rate’ suggested that employing the latest oocyte cryopreservation techniques could both foster individual women’s reproductive autonomy and impact ...
Lee, Geok Ling, Blyth, E., Yee, Samantha, Blyth, Eric, Yee, S., Lee, G.L.   +5 more
core  

Legal problems arising from the application of assisted reproductive techniques

, 2022
Yıllar içerisinde infertilite sıklığındaki kademeli artış ile birlikte doğal yollardan çocuk sahibi olamayan kişilerin üreme hakkı, soybağını sürdürme hakkı gibi en temel kişilik haklarından mahrum kalması; toplumun ihtiyaçları ile örtüşen bir gelişim
Şen, Embiye
core  

Assisted reproductive techniques do not impact late neurodevelopmental outcomes of preterm children. [PDF]

Front Pediatr, 2023
Lefebvre T, Flamant C, Olivier M, Gascoin G, Bouet PE, Roze JC, Barrière P, Fréour T, Muller JB.   +8 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Ethical Considerations in Assisted Reproductive Techniques: A Scoping Review [PDF]

Journal of Mazandaran University of Medical Sciences
Background and purpose: Fertility has long been recognized as a fundamental aspect of human life because of its role in the continuation of generations and the fulfillment of parenthood.
Samira Malayen, Nasim Yousefi Ghand Ali, Zohreh Shahhosseini   +2 more
doaj  

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Assisted Reproductive Technology Surveillance \u2014 United States, 2002

This report provides state-specific information on ART procedures performed in the United States in 2002. It compares ART birth outcomes with outcomes for all infants born in the United States in 2002. It includes data from the 50 states, the District of

core  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source