Results 51 to 60 of about 6,500,274 (300)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Assisted Reproductive Techniques and Cardiovascular Risk
Journal of the American College of Cardiology, 2019 We read with great interest the study by Meister et al. [(1)][1] in a recent issue of the Journal . In this longitudinal study of children conceived by assisted reproductive techniques (ART), the investigators detected signs of premature vascular aging and also a significant 6-fold increase in ...
Naga Venkata, Pothineni +2 more
openaire +2 more sources
Salud ColectivaSurrogacy is a practice that generates controversy, especially in contexts where regulation is scarce or nonexistent. In Argentina, although there is no specific legislation, this practice involves significant judicial mediation and various legal ...
Lucía Ariza, Natacha Salomé Lima
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Psychosocial Problems during Infertility Treatment [PDF]
Psikiyatride Güncel Yaklaşımlar, 2013 Infertility is a complex situation crisis which is often psychologically-threatening and emotionally stressful for both partners as well as economically expensive and causes physical pain due to the operations performed for diagnosis and treatment ...
Nurcan Kirca, Turkan Pasinlioglu
doaj
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Role of hysteroscopy prior to assisted reproductive techniques
Journal of Gynecological Endoscopy and Surgery, 2009 There have been numerous advances in the area of assisted reproduction. Among the various reasons of implantation failure, intrauterine lesions play an important role.The aim of the present study is to evaluate the role of hysteroscopy prior to any assisted reproductive technique.It is a retrospective study of 292 women who attended our infertility ...
Palshetkar, Nandita +2 more
openaire +3 more sources
Below population replacement fertility rates: Can assisted reproductive technology (ART) help reverse the trend? [PDF]
, 2013 Objective: This paper considers the potential contribution that assisted reproductive technology (ART) may make to population replenishment in countries that have experienced extended periods of below-population-replacement Total Fertility Rates (TFR ...
Blyth, Eric
core +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Journal of Human Reproductive Sciences, 2012 Development of ART has great benefit for millions of couples all over the world and with falling fertility rate there are a growing numbers of children born with the help of ART, it is important to investigate potential risks to these children. IVF-ICSI pregnancies are associated with higher risk for multiple gestation, preterm labor and low birth ...
Sunita Tandulwadkar +2 more
openaire +3 more sources