Results 61 to 70 of about 47,366 (258)

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Working Motivation Sources and Related Factors of Embryologists

open access: yesFertility & Reproduction
Introduction: As the need for assisted reproductive technologies (ART) continues to grow, the workload for embryologists has significantly increased in recent years.
Nga T. T. Do   +4 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

The relationship of sociocultural beliefs and infertile couples' attitude toward reproductive donation: A descriptive-correlational study

open access: yesInternational Journal of Reproductive BioMedicine, 2019
Background There are controversial views on accepting a reproductive donation in the world. Objective This study aimed to determine the relationship between the sociocultural beliefs and infertile couples' attitude toward reproductive ...
Robab Latifnejad Roudsari   +2 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Cytogenetic Findings in Couples who Are Candidates for Assisted Reproductive Techniques [PDF]

open access: yesCell Journal, 2009
Objective: The present retrospective study aims at identifying the prevalence ofchromosomal abnormalities in a population of couples who are candidates for assistedreproductive techniques.Materials and Methods: Cytogenetic analysis was performed ...
I. Salahshourifar   +2 more
doaj  

Outcome of twin pregnancies conceived after assisted reproductive techniques

open access: yesJournal of Human Reproductive Sciences, 2008
Context : There is a continuous controversy regarding the obstetric perinatal outcome of twin pregnancies conceived after assisted reproductive techniques (ART). There is an ongoing discussion whether theses parameters may show poorer results as compared
A Baxi, M Kaushal
doaj   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

open access: yesFEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

The Relationship between First Trimester 25-Hydroxyvitamin D3 Levels and Second Trimester Femur Length and Their Effects on Birth Weight and Length at Birth: A Preliminary Study

open access: yesObstetrics and Gynecology International, 2019
Objective. The main goal of our study was to assess relationships between first trimester 25-hydroxyvitamin D3 levels and infant birthweight and length at birth. Materials and Methods. We conducted a study over our medical records of 154 live-term births
Elif Ganime Aydeniz   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy