Results 81 to 90 of about 6,500,274 (300)
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Cytogenetic Findings in Couples who Are Candidates for Assisted Reproductive Techniques [PDF]
Objective: The present retrospective study aims at identifying the prevalence ofchromosomal abnormalities in a population of couples who are candidates for assistedreproductive techniques.Materials and Methods: Cytogenetic analysis was performed ...
I. Salahshourifar +2 more
doaj
2010 Assisted Reproductive Technology National Summary Report [PDF]
The data for this national report come from the 443 fertility clinics in operation in 2010 that provided and verified data on the outcomes of all ART cycles started at their clinics.
core
Assisted reproduction has recently entered the field of interest of researchers and physicians and has become an open topic of research. Considering the 1.5 million babies born with assisted reproductive techniques today, we can also understand why this ...
Yapıcı, Tunahan, Aghayeva, Aynura
core
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
2014 Assisted Reproductive Technology National Summary Report [PDF]
The data for this national report come from the 458 fertility clinics in operation in 2014 that provided and verified data on the outcomes of all ART cycles started in their clinics. Of the 208,604 ART cycles performed in 2014 at these reporting clinics,
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CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
2012 Assisted Reproductive Technology National Summary Report [PDF]
The data for this national report come from the 456 fertility clinics in operation in 2012 that provided and verified data on the outcomes of all ART cycles started in their clinics. Of the 176,247 ART cycles performed in 2012 at these reporting clinics,
core
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Background This study investigates how clinical factors and hormonal levels affect oocyte retrieval in modified natural cycles, aiming to improve understanding and enhance treatment protocols.Methods A retrospective analysis of data from 306 women ...
Yonghuan Lv +7 more
doaj +1 more source

