Results 121 to 130 of about 52,542 (290)

Accessibility of Vendor-Created Video Tutorials for People with Disabilities [PDF]

, 2016
Many video, screencast, webinar, or interactive tutorials are created and provided by vendors for use by libraries to instruct users in database searching.
Oud, Joanne
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Estimating need and coverage for five priority assistive products: a systematic review of global population-based research. [PDF]

BMJ Glob Health, 2022
Danemayer J, Boggs D, Delgado Ramos V, Smith E, Kular A, Bhot W, Ramos-Barajas F, Polack S, Holloway C.   +8 more
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Translation of the Rapid Assistive Technology Assessment Tool and Assessing Its Face Validity [PDF]

Journal of Rehabilitation
Objective The global demand for assistive technology (AT) is extensive, with over 2.5 billion people requiring one or more assistive devices. This number is expected to increase to 3.5 billion by 2050.
Hossein Gerivani, Amirhossein Takian, Haniye Sadat Sajadi, Marzieh Shirazikhah, Mohammad Taghi Joghataei   +4 more
doaj  

Assessing the value of the information provision for enhancing the autonomy of mobility impaired users. Madrid pilot Site Study. [PDF]

, 2008
A City is the space where every person acquires the citizen condition, which demands access to multiple services and facilities, and develops social relations in a free and equal condition of options.
Chamorro Mata, Javier, Hoz Sánchez, Daniel de la, Pastor Sanz, Laura, Sastre González, Julián, Ventoso, Lara, Villalar González, Juan Luis   +5 more
core   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Exploring the Use of Washington Group Questions to Identify People with Clinical Impairments Who Need Services including Assistive Products: Results from Five Population-Based Surveys. [PDF]

Int J Environ Res Public Health, 2022
Boggs D, Kuper H, Mactaggart I, Bright T, Murthy G, Hydara A, McCormick I, Tamblay N, Alvarez ML, Atijosan-Ayodele O, Yonso H, Foster A, Polack S.   +12 more
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

User satisfaction and dissatisfaction with assistive technology devices and services in India

Scientific Reports
User satisfaction with Assistive Technology (AT) is one of the crucial factors in the success of any AT service. The current study aimed to estimate satisfaction with AT and the reasons for dissatisfaction and unsuitability among persons with functional ...
Suraj Singh Senjam, Souvik Manna, Jeewan Singh Titiyal, Anil Kumar, Jugal Kishore   +4 more
doaj   +1 more source