Results 41 to 50 of about 10,756 (248)
Within the field of products for autism spectrum disorder, one of the main research areas is focused on the development of assistive technology. Mid and high-tech products integrate interactive and smart functions with multisensory reinforcements, making
Raquel Cañete, Estela Peralta
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Global availability of guidelines related to assistive technology: a scoping review
BackgroundGiven the rising global demand for assistive technology, predicted to encompass 3.5 billion people by 2050, understanding the availability of guidelines governing its use and identifying potential gaps is paramount.ObjectiveThis scoping review ...
Wei Zhang, Johan Borg
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Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Assistive technology and public policies in Brazil
Assistive Technology is not widespread in Brazil. Advances have occurred gradually through achievements in the legal area and the promotion of research and development.
Paula Alessandra Lima Santos Bastos +4 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Objective To investigate the current status of assistive device adaptation among people with dysfunction in China, identify unmet assistive needs for assistive products, and determine key factors influencing attitudes toward assistive device use. Methods
LIU Chen +3 more
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Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Home modifications that increase stair accessibility of existing housing stock are significant for older adults who want to age in place. This sequential mixed-methods study investigated older adults’ attitudes toward and intentions to use currently ...
Elif Tural, Danni Lu, D. Austin Cole
doaj +1 more source

