Results 41 to 50 of about 91,889 (285)

Intelligent sensors in assistive systems for deaf people: a comprehensive review [PDF]

PeerJ Computer Science
This research aims to conduct a systematic literature review (SLR) on intelligent sensors and the Internet of Things (IoT) in assistive devices for the deaf and hard of hearing.
Caio César Sabino Soares, Luis Augusto Silva, Anita Fernandes, Gabriel Villarrubia González, Valderi R.Q. Leithardt, Wemerson Delcio Parreira   +5 more
doaj   +2 more sources

Transformational government and assistive web base technologies [PDF]

, 2009
Transformational government has been on the European agenda for several years. However, progress towards realising the full potential of ICT to transform public services for older adults with age related cognitive impairments has been very limited ...
Elliman, T, Fernando, S, Lines, L, Money, A   +3 more
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Disability-aware adaptive and personalised learning for students with multiple disabilities [PDF]

, 2017
Purpose The purpose of this paper is to address how virtual learning environments (VLEs) can be designed to include the needs of learners with multiple disabilities.
Brayshaw, Mike, Nganji, Julius T.
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Development of Assistive Robots Using International Classification of Functioning, Disability, and Health: Concept, Applications, and Issues

Journal of Robotics, 2013
Many assistive robots for elderly and disabled people have been developed in the past few decades. However, very few of them became commercially available.
Hideyuki Tanaka, Masahiro Yoshikawa, Eimei Oyama, Yujin Wakita, Yoshio Matsumoto   +4 more
doaj   +1 more source

Implications of the Information Technology Revolution for People with Disabilities [PDF]

, 2000
The paper focuses on opportunities for the integration of persons with different types of disabilities in the information technology (IT) labour market.
Bonney, Martha, Bruyere, Susanne M, Dr., Ruiz-Quintanilla, S. Antonio   +2 more
core   +1 more source