Results 51 to 60 of about 91,460 (267)

Therapeutic robots for post-stroke rehabilitation

open access: yesMedical Review
Stroke is a prevalent, severe, and disabling health-care issue on a global scale, inevitably leading to motor and cognitive deficits. It has become one of the most significant challenges in China, resulting in substantial social and economic burdens.
Hong Ronghua   +4 more
doaj   +1 more source

Documenting Downloadable Assistive Technologies [PDF]

open access: yes, 2016
This major research project explores Downloadable Assistive Technologies (DAT) and the possibilities as well as the limitations of publishing and fabricating DAT through online 3D printing communities. A design probe was used for this research within the
Charbonneau, Erica
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Effects of brain-computer interface based training on post-stroke upper-limb rehabilitation: a meta-analysis

open access: yesJournal of NeuroEngineering and Rehabilitation
Background Previous research has used the brain-computer interface (BCI) to promote upper-limb motor rehabilitation. However, the results of these studies were variable, leaving efficacy unclear. Objectives This review aims to evaluate the effects of BCI-
Dan Li   +8 more
doaj   +1 more source

Skin-Mounted RFID Sensing Tattoos for Assistive Technologies [PDF]

open access: yes, 2014
UHF RFID technology is presented that can facilitate new passive assistive technologies. Tongue control for human computer interfaces is first discussed where a tag is attached to the hard palate of the mouth and the tag turn-on power is observed to vary
Batchelor, John C.   +3 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Posthumanism and assistive technologies

open access: yesTrabalhos em Linguística Aplicada, 2019
In this paper, we elaborate on the consequences of a post-humanist perspective to the problem of physical disability by approaching the use of assistive technologies (AT) by disabled people as the introduction of a low-tech cyborg in the world.
Elizabeth Kath   +2 more
doaj  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Assistive Technology to Promote Communication and Social Interaction for People With Deafblindness: A Systematic Review

open access: yesFrontiers in Education, 2020
Background: People with deafblindness experience stigmatization, exclusion, and isolation. Due to complex communication challenges, feelings of isolation and exclusion can increase. However, assistive technology can change these negative outcomes.
Vernandi Dyzel   +4 more
doaj   +1 more source

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