Results 81 to 90 of about 91,889 (285)
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Ability or disability – design for whom?
Scandinavian Journal of Disability Research, 2013 The dilemma addressed is how private homes and their residents change when the home becomes a hybrid of both workspace and private space. When assistive technologies designed for institutions enter the home, the everyday practices of disabled persons and
Søsser Brodersen, Hanne Lindegaard
doaj +1 more source
In-home and remote use of robotic body surrogates by people with profound motor deficits [PDF]
, 2019 By controlling robots comparable to the human body, people with profound motor deficits could potentially perform a variety of physical tasks for themselves, improving their quality of life.
Grice, Phillip M., Kemp, Charles C.
core +3 more sources
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Use of personal call alarms among community-dwelling older people. [PDF]
, 2012 Having a fall and then lying on the floor for an hour or more is known as a ‘long lie’, which are associated with serious injury and an elevated risk of admission to hospital, long-term care, and death.
Brownsell +20 more
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Assistive Technology for Individuals with Special Seeds [PDF]
Annals of Dunarea de Jos University. Fascicle I : Economics and Applied Informatics, 2015 Disabled people face barriers in performing their various activities, including teaching. By using assistive technologies for different activities, people with disabilities may be able to perform a wider range of tasks independently.
Adrian Lupasc
doaj
Towards solutions for assistive technology [PDF]
Introduction What is assistive technology? The agreed World Health Organisation definition is "Assistive technology can be defined as “any piece of equipment, or product, whether it is acquired commercially, modified, or customized, that is used to ...
National Disability Insurance Agency
core
Technology and Caregiving: Emerging Interventions and Directions for Research. [PDF]
, 2020 An array of technology-based interventions has increasingly become available to support family caregivers, primarily focusing on health and well-being, social isolation, financial, and psychological support.
Apesoa-Varano, Ester Carolina +3 more
core
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source