Results 251 to 260 of about 1,545,557 (316)

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Antimicrobial use and stewardship activities in Swiss long-term care facilities: data from a national point-prevalence survey. [PDF]

open access: yesAntimicrob Resist Infect Control
Toppino S   +9 more
europepmc   +1 more source

Trace Elements in the Pancreas: From Physiological Homeostasis to the Pathogenesis of Diabetes, Pancreatitis, and Cancer-A Review. [PDF]

open access: yesLife (Basel)
Bryliński Ł   +11 more
europepmc   +1 more source

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