Results 131 to 140 of about 5,206,814 (298)

The Y-box factor ZONAB/DbpA associates with GEF-H1/Lfc and mediates Rho-stimulated transcription

, 2009
Epithelial tight junctions recruit different types of signalling proteins that regulate cell proliferation and differentiation. Little is known about how such proteins interact functionally and biochemically with each other.
Leefa Chong San, I.V., Isabelle V Leefa Chong San, Maria S Balda, Saima Aijaz, Karl Matter, Nie, M., Aijaz, S., Mei Nie, Balda, M.S., Matter, K.   +9 more
core   +1 more source

Prevalence of Diabetic Retinopathy and Its Associated Factors among Diabetic Patients at Debre Markos Referral Hospital, Northwest Ethiopia, 2019: Hospital-Based Cross-Sectional Study

Diabetes, Metabolic Syndrome and Obesity, 2020
Melkamu Tilahun,1 Teshome Gobena,2 Diriba Dereje,2 Mengistu Welde,2 Getachew Yideg3 1Department of Biomedical Sciences (Medical Physiology), College of Medicine and Health Sciences, Debre Markos University, Debre Markos, Ethiopia; 2Department of ...
Tilahun M, Gobena T, Dereje D, Welde M, Yideg G   +4 more
doaj  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

REST, not REST4, is a risk factor associated with radiotherapy plus chemotherapy efficacy in glioma

, 2018
Cuilin Li,1,2 Hecun Zou,1–3 Zhifei Wang,4 Xinyue Tang,1,2 Xitang Fan,4 Ke Zhang,1,2 Jianqiu Liu,1,2 Zhi Li1,2 1Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, China; 2Institute of Clinical Pharmacology ...
Zou H, Liu J, Fan X, Li Z, Li C, Zhang K, Wang ZF, Tang X   +7 more
core  

Prevalence of Bottle‐Feeding Practice and Associated Factors Among Mothers of Children Under Five in the World, 2024: Systematic Review and Meta‐Analysis

Reproductive, Female and Child Health
Background Child‐feeding practices, particularly breastfeeding, significantly impact children's health and survival. However, bottle feeding, although historically practiced, presents numerous disadvantages affecting optimal child nutrition and health ...
Demis Getachew, Eyob Getachew, Amlaku Nigusie Yirsaw, Habtamu Semagne Ayele, Getnet Alemu Andargie, Abriham Adane Lakew, Abiyu Abadi Tareke, Negesse Shiferaw Zeru, Gebeyehu Lakew   +8 more
doaj   +1 more source

Abnormal Glucose Metabolism and Associated Risk Factors Among Adults in Mekelle City, Ethiopia

Diabetes, Metabolic Syndrome and Obesity, 2020
Gebremedhin Gebreegziabiher,1 Tefera Belachew,2 Dessalegn Tamiru2 1Department of Human Nutrition, School of Public Health, College of Medicine and Health Sciences, Adigrat University, Adigrat, Ethiopia; 2Department of Nutrition and Dietetics, Faculty of ...
Gebreegziabiher G, Belachew T, Tamiru D
doaj  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Decreased Epidermal Growth Factor (EGF) Associated with HMGB1 and Increased Hyperactivity in Children with Autism

, 2013
Background Autism spectrum disorders (ASDs), characterized by impaired social interactions and deficits in verbal and nonverbal communication, are thought to affect 1 in 88 children in the United States.
Anthony J. Russo
core   +1 more source

Prevalence of Chronic Kidney Disease and Associated Factors Among Adult HIV/AIDS Patients on HAART in Hiwot Fana Comprehensive Specialized Hospital, Eastern Ethiopia: A Cross‐Sectional Study

Health Science Reports
Background and Aims Chronic kidney disease related to human immunodeficiency virus infection has become a significant concern in sub‐Saharan Africa, primarily due to the high prevalence of the virus, along with delays in diagnosis and the initiation of ...
Gada Diba, Ahmedmenewer Abdu, Ephrem Tefera Solomon, Winner Kucha   +3 more
doaj   +1 more source