Results 131 to 140 of about 10,769,756 (304)
Factor Substitution and Unobserved Factor Quality in Nursing Homes [PDF]
This paper studies factor substitution in one important sector: the nursing home industry. Specifically, we measure the extent to which nursing homes substitute materials for labor when labor becomes relatively more expensive.
David C. Grabowski +2 more
core
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Background Child‐feeding practices, particularly breastfeeding, significantly impact children's health and survival. However, bottle feeding, although historically practiced, presents numerous disadvantages affecting optimal child nutrition and health ...
Demis Getachew +8 more
doaj +1 more source
Abnormal Glucose Metabolism and Associated Risk Factors Among Adults in Mekelle City, Ethiopia
Gebremedhin Gebreegziabiher,1 Tefera Belachew,2 Dessalegn Tamiru2 1Department of Human Nutrition, School of Public Health, College of Medicine and Health Sciences, Adigrat University, Adigrat, Ethiopia; 2Department of Nutrition and Dietetics, Faculty of ...
Gebreegziabiher G, Belachew T, Tamiru D
doaj
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Background and Aims Chronic kidney disease related to human immunodeficiency virus infection has become a significant concern in sub‐Saharan Africa, primarily due to the high prevalence of the virus, along with delays in diagnosis and the initiation of ...
Gada Diba +3 more
doaj +1 more source
Abinet Teshome,1 Mustefa Glagn,2 Mulugeta Shegaze,2 Beemnet Tekabe,2 Asmare Getie,3 Genet Assefa,3 Dinkalem Getahun,3 Tesfaye Kanko,1 Tamiru Getachew,4 Nuhamin Yenesew,5 Zebene Temtmie,5 Kabtamu Tolosie6 1Department of Biomedical Science, School of ...
Teshome A +11 more
doaj
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

