Results 111 to 120 of about 5,206,814 (298)

The Morbidity and Associated Factors of Depression in Caregivers of Patients with Depressive Disorder

Neuropsychiatric Disease and Treatment, 2023
Yu Lee,1 Pao-Yen Lin,1 Yu-Chi Huang,1 Nien-Mu Chiu,1 Chi-Fa Hung,1 Liang-Jen Wang2 1Department of Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan; 2Department of Child and Adolescent ...
Lee Y, Lin PY, Huang YC, Chiu NM, Hung CF, Wang LJ   +5 more
doaj  

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Clinical practice guidelines for the management of atypical haemolytic uraemic syndrome in the United Kingdom

, 2010
Atypical haemolytic uraemic syndrome (aHUS) is associated with a poor prognosis with regard to survival at presentation, recovery of renal function and transplantation.
Sam Machin, ?, ?, Machin, Sam, Tim H. J. Goodship, Goodship, Tim H J, Stephen J. Wigmore, Taylor, C Mark, Wigmore, Stephen J, C. Mark Taylor   +8 more
core   +1 more source

Assessment of the magnitude, economic impact, and factors associated with expired veterinary pharmaceuticals in animal health facilities in South Wollo, Ethiopia

Frontiers in Veterinary Science
BackgroundThe issue of veterinary pharmaceutical expiration is a significant concern in animal health facilities globally. The existence of veterinary pharmaceutical expiration can be mainly associated with inadequate inventory control, store management,
Yesuneh Tefera Mekasha, Ermias Belay Mekonnen, Abebe Tesfaye Gessese, Kassahun Berrie, Achenef Melaku Beyene, Bereket Dessalegn   +5 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Prevalence of Metabolic Syndrome and Factors Associated With It Among Adults of West Gojjam: A Community-Based Cross-Sectional Study

Diabetes, Metabolic Syndrome and Obesity, 2021
Bizuayehu Walle,1 Kidist Reba,2 Yamrot Debela,3 Kassahun Tadele,4 Fantahun Biadglegne,5 Hordofa Gutema3 1Department of Physiology, College of Medicine and Health Sciences, Bahir Dar University, Bahir-Dar, Ethiopia; 2Department of Adult Health Nursing ...
Walle B, Reba K, Debela Y, Tadele K, Biadglegne F, Gutema H   +5 more
doaj  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Chronic bronchitis is an independently associated factor for more symptom and high-risk groups

, 2016
Joon Young Choi,1 Hyoung Kyu Yoon,2 Seoung Ju Park,3 Yong Bum Park,4 Kyeong-Cheol Shin,5 Ju Ock Na,6 Kwang Ha Yoo,7 Ki-Suck Jung,8 Young Kyoon Kim,1 Chin Kook Rhee1 1Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal ...
Choi JY, Na JO, Jung KS, Kim YK, Rhee CK, Shin KC, Yoo KH, Yoon HK, Park SJ, Park YB   +9 more
core  

Dynamic changes in DNA methylation of stress-associated genes (OXTR, BDNF) after acute psychosocial stress [PDF]

, 2012
Environmentally induced epigenetic alterations are related to mental health. We investigated quantitative DNA methylation status before and after an acute psychosocial stressor in two stress-related genes: oxytocin receptor (OXTR) and brain-derived ...
Dempster, E., Dempster, Emma, Unternaehrer, Eva, Lieb, Roselind, Meyer, A. H., Unternaehrer, E., Luers, P., Mill, J., Staehli, S., Hellhammer, D. H., Meyer, Andrea H., Lieb, R., Meinlschmidt, G., Staehli, Simon, Mill, John, Hellhammer, Dirk H., Meinlschmidt, Gunther   +16 more
core   +1 more source