Results 91 to 100 of about 5,206,814 (298)

Clinical perspective on oxidative stress in sporadic amyotrophic lateral sclerosis

, 2013
Sporadic amyotrophic lateral sclerosis (ALS) is one of the most devastating neurological diseases; most patients die within 3 to 4 years after symptom onset.
Mitsumoto H, Santella RM, Factor-Litvak, Pam, Mitsumoto, Hiroshi, Factor-Litvak P, D'Amico E, Santella, Regina M., D'Amico, Emanuele   +7 more
core   +1 more source

Factors associated with tuberculosis in cattle in the urban and peri-urban areas of Ouagadougou, Burkina Faso, 2021

Journal of Interventional Epidemiology and Public Health
Introduction: Bovine tuberculosis is endemic in Burkina Faso. It is a chronic zoonosis with a significant health and economic impact. Studies carried out on both sides of the country show the existence of bovine tuberculosis with a high prevalence ...
Djenebou Diakité, Laibané Dieudonné Dahourou, Djibril Barry, Pauline Kiswendsida Yanogo, Yoda Hermann, Jéan Kaboré, Brice Wilfrid Bicaba, Nicolas Meda, Lamouni Habibata Zerbo, Samba Thioub, Lalidia Bruno Ouoba, Sayouba Ouédraogo, Désiré Nana   +12 more
doaj   +1 more source

Prevalence of Primary Tooth Extraction and Its Associated Factors Among Under-Five-Year-Old Children in Debre Tabor Town, North-Central Ethiopia: Community-Based Cross-Sectional Study

International Journal of General Medicine, 2023
Gashaw Mekete,1 Getaneh Mulualem,2 Selam Fisiha Kassa2 1Department of Pediatrics and Child Health Nursing, Debre Tabor Health Science College, Debre Tabor, Ethiopia; 2Department of Pediatrics and Child Health Nursing, School of Nursing, College of ...
Mekete G, Mulualem G, Kassa SF
doaj  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Spontaneous bleeding in a patient with malignant lymphoma: A case of acquired hemophilia [PDF]

, 2000
Background: Acquired hemophilia is a rare condition which can be associated with lymphoproliferative disease. Case Report: Eleven yea rs after the diagnosis of immunocytoma had been made, a 72-year-old man developed a high-titer factor VIII inhibitor. At
Brack, N., Gesierich, Wolfgang, Pohlmann, H., Munker, Reinhold, Geiersberger, U., Hartenstein, R.   +5 more
core   +1 more source

Correlation of systemic immune inflammation index and systemic inflammatory response index with the severity of Parkinson’s disease

Frontiers in Neurology
BackgroundWhile the significance of inflammation in Parkinson’s disease (PD) pathogenesis has been established, the relevance of emerging hematological markers such as the systemic immune-inflammation index (SII) and systemic inflammatory response index (
Fangyi Li, Zhen Wang, Mingzhu Deng, Jian Peng, Guohua He, Yangping Tong, Wei Xu, Tieqiao Feng, Kangping Song   +8 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Sustained high-level expression of human factor IX (hFIX) after liver-targeted delivery of recombinant adeno-associated virus encoding the hFIX gene in rhesus macaques

, 2002
The feasibility, safety, and efficacy of liver-directed gene transfer was evaluated in 5 male macaques (aged 2.5 to 6.5 years) by using a recombinant adeno-associated viral (rAAV) vector (rAAV-2 CAGG-hFIX) that had previously mediated persistent ...
Hanawa, H, Ng, CYC, Mandrell, TD, Vanin, EF, Nathwani, AC, Hu, Y, Davidoff, AM, Hoffer, FA, Zhou, J, Slaughter, C, Nikanorov, A, Lozier, JN, Nienhuis, AW   +12 more
core  

The splicing factor proline-glutamine rich (SFPQ/PSF) is involved in influenza virus transcription.

, 2011
The influenza A virus RNA polymerase is a heterotrimeric complex responsible for viral genome transcription and replication in the nucleus of infected cells. We recently carried out a proteomic analysis of purified polymerase expressed in human cells and
Juan Ortín, Landeras-Bueno, Sara, Jorba, N, Sara Landeras-Bueno, Ortín Juan, Pérez-Cidoncha, Maite, Pérez-Cidoncha, M, Núria Jorba, Landeras-Bueno Sara, Pérez-Cidoncha Maite, Landeras-Bueno, S, Ortín, J, Ortín, Juan, Jorba, Núria, Maite Pérez-Cidoncha, Jorba Núria   +15 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source