Results 81 to 90 of about 16,335,760 (244)

Macrophage-derived insulin-like growth factor-1 is a key neurotrophic and nerve-sensitizing factor in pain associated with endometriosis [PDF]

, 2019
Endometriosis is a common incurable inflammatory disorder that is associated with debilitating pelvic pain in women. Macrophages are central to the pathophysiology of endometriosis: they dictate the growth and vascularization of endometriosis lesions and
Sarginson, Alexandra, Saunders, Philippa T. K.; id_orcid, Forster, Rachel, Hogg, Chloe, Horne, Andrew W., Velichkova, Atanaska, Dorning, Ashley, Saunders, Philippa, Greaves, Erin   +8 more
core   +1 more source

Identifying Patterns of Hospitalizations Among Childhood Cancer Survivors: A Population‐Based Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Childhood cancer survivors (CCSs) experience more hospitalizations than the general population. We aimed to identify distinct hospitalization patterns among Queensland CCSs and the associated characteristics. Methods Cases (aged ≤14 years) diagnosed between 1995 and 2019 while residents of Queensland were identified through the ...
Hai Pham, Teyl Engstrom, Peter Baade, Natalie Bradford, Sarah Pont, Louise Marquart‐Wilson, Natasha Nassar, Jason D. Pole   +7 more
wiley   +1 more source

Clinical perspective on oxidative stress in sporadic amyotrophic lateral sclerosis

, 2013
Sporadic amyotrophic lateral sclerosis (ALS) is one of the most devastating neurological diseases; most patients die within 3 to 4 years after symptom onset.
Mitsumoto H, Santella RM, Factor-Litvak, Pam, Mitsumoto, Hiroshi, Factor-Litvak P, D'Amico E, Santella, Regina M., D'Amico, Emanuele   +7 more
core   +1 more source

Activation of transforming growth factor beta by malaria parasite-derived metalloproteinases and a thrombospondin-like molecule [PDF]

, 2003
Much of the pathology of malaria is mediated by inflammatory cytokines (such as interleukin 12, interferon gamma, and tumor necrosis factor alpha), which are part of the immune response that kills the parasite.
Riley, Eleanor M, Sultan, Ali A, J. Brian de Souza, de Souza, J Brian, Eleanor M. Riley, Corran, Patrick H, Patrick H. Corran, Omer, Fakhreldin M, Riley, EM, Sultan, AA, Corran, PH, Ali A. Sultan, Omer, FM, de Souza, JB, Fakhreldin M. Omer   +14 more
core   +1 more source

Pathogenic characteristics and factors associated with multidrug-resistant bacterial infections after perianal abscess surgery

Frontiers in Surgery
ObjectiveThis study aims to describe the pathogenic characteristics of multidrug-resistant (MDR) bacterial infections after perianal abscess surgery and explore its associated factors.MethodsThis retrospective study included 246 adult patients who ...
Bingjie Wang, Xujing Wei, Wanli Ma, Xiangsheng Wang, Binghui Hu, Yefang Zhao   +5 more
doaj   +1 more source

Classical Complement Pathway Inhibition in a Pediatric Patient With Refractory Immune Thrombocytopenia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric refractory immune thrombocytopenia (rITP) is generally characterized by persistent thrombocytopenia and failure to achieve a sustained response to multiple standard therapies. We report a 4‐year‐old female with congenital tufting enteropathy, post‐intestinal transplant patient on immunosuppressants, who developed severe rITP ...
Sarah Hsieh, Susmita Sarangi, Caileigh Pudela, Catherine M. Broome, Tara K. Suntum   +4 more
wiley   +1 more source

Clinical practice guidelines for the management of atypical haemolytic uraemic syndrome in the United Kingdom [PDF]

, 2010
Atypical haemolytic uraemic syndrome (aHUS) is associated with a poor prognosis with regard to survival at presentation, recovery of renal function and transplantation.
Sam Machin, ?, ?, Machin, Sam, Tim H. J. Goodship, Goodship, Tim H J, Stephen J. Wigmore, Taylor, C Mark, Wigmore, Stephen J, C. Mark Taylor   +8 more
core   +1 more source

Clinical characteristics and mortality risk of sarcopenia in interstitial lung disease: a systematic review and meta-analysis

Frontiers in Medicine
ObjectiveSarcopenia, prevalent in interstitial lung disease (ILD), increases the risk of poor outcomes. This study aimed to define the clinical characteristics of ILD patients with sarcopenia (ILD-S) and quantify sarcopenia's impact on mortality ...
Lijuan Zhou, Xuan Wang, Weiwei Yuan, Yahui Yang, Ting Lu, Lu Guo, Xing He, Xing He   +7 more
doaj   +1 more source

Evidence‐Based Clinical Practice Guidelines for the Management of Pediatric Febrile Neutropenia: Resource‐Sensitive Recommendations for the Asian Continent

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Febrile neutropenia (FN) is a frequent and serious complication in children receiving cancer therapy. Standardizing FN management across Asia is challenging due to variable healthcare infrastructure, diagnostic capacity, and infection patterns; however, it could improve resource use and patient outcomes.
Joliza Patricia Cañeba, Shweta Bansal, Tea Reljic, Allyne Montecillo‐Aguelo, Hamidah Alias, Farrah Amaranto, Maria Stella Aquino‐Calingasan, Bambang Ardianto, Eggi Arguni, Sally Blair, Thi Tam Dang, Maria Beatriz Gepte, Samanmalee Gunasekara, Andini Handayani, Miriam Kimpo, Catherine G. Lam, Nawachai Lertvivatpong, Sergio Licona, Ana Loseo, Ratha Mlis, Vivian Moreno Berrio, Nguyen Hoai Anh, Anna Lisa Ong‐Lim, Ha Thu Pham, Krishna Sagar Sharma, Bun Sereyleak, Sally Jane G. Velasco‐Aro, Su Yadana, Ambuj Kumar, Sheena Mukkada   +29 more
wiley   +1 more source

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye, Chimezie Okwuonu, Evelyn Idam, Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Zinnah Aloziem, Blossom Amamchukwu, Patience Elimia, Mkpoikanabasi Obot‐Obot, Henry Mbakwe, Praises Maduagwuna, Olatunji Akinrodoye, Chiamaka Anyanwu, Benjamin Anyanwu, Adedamola Akinsiku, Oluwatoyin A. Akinsiku, Muzamil O. Hassan, Fatiu A. Arogundade, Olalekan E. Ojo, Homayemem Weli, Jesupelumi Adenihun, Aderemi Adelaja, Ebun Bamgboye, Olalekan Olatise, Ade E. Faponle, Ayoola Odeyemi, Michael Muoka, Stephen Asaolu, Qudrat Busari, Blessing Dawudu, Michael Naiyeju, Rasheed A. Balogun   +33 more
wiley   +1 more source