Results 71 to 80 of about 5,206,814 (298)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

A survey of prevalence of constipation and its associated factors in postmenopausal Women referred to health centers of Roudan -2015 [PDF]

Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2017
Introduction: Physical and mental physiological changes associated with menopause is affected all the female body systems including the gastrointestinal tract that In fact, one of digestive disorders are constipation which in severe cases quality of life
Kobra Kamali, Shahnaz Glian Tehrani, Mojdeh Banaei, Mansoureh Jamshidi, Shokrollah Mohseni   +4 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Activation of transforming growth factor beta by malaria parasite-derived metalloproteinases and a thrombospondin-like molecule [PDF]

, 2003
Much of the pathology of malaria is mediated by inflammatory cytokines (such as interleukin 12, interferon gamma, and tumor necrosis factor alpha), which are part of the immune response that kills the parasite.
Riley, Eleanor M, Sultan, Ali A, J. Brian de Souza, de Souza, J Brian, Eleanor M. Riley, Corran, Patrick H, Patrick H. Corran, Omer, Fakhreldin M, Riley, EM, Sultan, AA, Corran, PH, Ali A. Sultan, Omer, FM, de Souza, JB, Fakhreldin M. Omer   +14 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

The role of hepatocyte growth factor/scatter factor in hepatoblastoma and hepatocellular carcinoma progression [PDF]

, 2006
Hepatocyte growth factor/scatter factor (HGF/SF) is a ubiquitously expressed molecule that elicits pleiotropic functions on epithelial cells, including mitogenic, motogenic, differentiating, angiogenic, and morphogenic effects. The receptor for HGF/SF is
Grotegut, Stefan
core   +1 more source

Clinical phenotypes and factor VII genotype in congenital factor VII deficiency

, 2005
To investigate the relationship between clinical phenotype, clotting activity (FVIIc) and FVII genotype, a multi-center study of factor VII (FVII) congenital deficiency with centralized genotyping and specific functional assays was carried out.
WULFF K, DOLCE A, PEYVANDI F, HERRMANN FH, MARIANI G, AUERSWALD G, SCHVED JF, BERNARDI, Francesco, INGERSLEV J, INTERNATIONAL FACTOR VII DEFICIENCY STUDY GROUP, BATOROVA A, ETRO, Daniela   +11 more
core   +2 more sources

Aortic isthmus flow reversal in fetal coarctation of the aorta and the associated factors

Acta Obstetricia et Gynecologica Scandinavica
Introduction The aim of this study was to investigate the presence of aortic isthmus flow reversal and its associated factors in fetuses with positive and false‐positive coarctation of the aorta (CoA) compared with normal controls.
Guihong Chen, Yongfeng Han, Congxin Sun, Wei Xiang, Wei Zhao, Pei Zhou, Tianxiao Yu, Zhuo Chen, Bulang Gao, Shuping Ge, Jie Mi   +10 more
doaj   +1 more source

High Prevalence of Clinically Active Trachoma and Its Associated Risk Factors Among Preschool-Aged Children in Arba Minch Health and Demographic Surveillance Site, Southern Ethiopia

Clinical Ophthalmology, 2020
Mustefa Glagn Abdilwohab, Zeleke Hailemariam Abebo School of Public Health, College of Medicine and Health Sciences, Arba Minch University, Arba Minch Town, EthiopiaCorrespondence: Mustefa Glagn Abdilwohab School of Public HealthCollege of Medicine and ...
Glagn Abdilwohab M, Hailemariam Abebo Z
doaj