Results 301 to 310 of about 15,575,930 (347)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Sarcopenia and Its Individual Traits Independently Predict Mortality in Patients on Dialysis: A Systematic Review and Meta-Analysis. [PDF]

J Cachexia Sarcopenia Muscle
Sabatino A, Guerra A, Baiocchi de Carvalho KM, Cuppari L, Carrero JJ, Stenvinkel P, Lindholm B, Avesani CM.   +7 more
europepmc   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Programmed Death Ligand 1 (PDL1) Expression in Neoadjuvant Triple-Negative Breast Cancer: Association With Chemotherapy Response and Residual Cancer Burden. [PDF]

Breast J
Hashmi AA, Wahid N, Mudassir G, Irfan M, Malik UA, Khan EY, Abu Bakar SM, Faridi N.   +7 more
europepmc   +1 more source

Causal association between dietary factors and Primary Biliary Cholangitis: A Mendelian randomization study. [PDF]

Medicine (Baltimore)
Luo H, Han L, He K, Chen K, Wei Q, Zhang C, Jiang L.   +6 more
europepmc   +1 more source

The association between smartphone addiction and creativity in Chinese college students: the chain mediating effects of depression and executive function. [PDF]

BMC Psychiatry
Li W, Liu J, Liu X, Ge Y, Wang Y, Zhang A.   +5 more
europepmc   +1 more source

Association between gout, hyperuricemia, and Parkinson's disease: a systematic review and meta-analysis. [PDF]

Eur J Med Res
Qtaishat FA, Alsufi MI, Yasin JA, Abunamoos A, Salomon I, Qutaishat S, Odat RM.   +6 more
europepmc   +1 more source

Association Between Gestational Weight Gain and Obstetric Anal Sphincter Injury. [PDF]

O G Open
Khademioore S, Khademioureh S, Sofi-Mahmudi A, Geoffrion R, D'Souza R, Muraca GM.   +5 more
europepmc   +1 more source

Corrigendum to "Association Between <i>rs920778</i> Polymorphisms and Cancer Risk: An Updated Meta-Analysis". [PDF]

Genet Res (Camb)
europepmc   +1 more source