Results 61 to 70 of about 5,612,897 (293)

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

Weighted functional linear regression models for gene-based association analysis.

PLoS ONE, 2018
Functional linear regression models are effectively used in gene-based association analysis of complex traits. These models combine information about individual genetic variants, taking into account their positions and reducing the influence of noise and/
Nadezhda M Belonogova, Gulnara R Svishcheva, James F Wilson, Harry Campbell, Tatiana I Axenovich   +4 more
doaj   +1 more source

Pediatric Oncology Nursing Competencies in Latin America and the Caribbean: A Scoping Review to Inform Practice, Education, and Research

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Nurses are central to cancer care for children and adolescents, yet no comprehensive synthesis has defined essential core competencies for pediatric oncology nursing (PON) practice internationally, particularly in Latin America and the Caribbean (LAC).
Luís Carlos Lopes‐Júnior, Edmara Bazoni Soares Maia, Soad Fuentes‐Alabí, Courtney E. Sullivan, Monnie Abraham, Mauricio Maza, Liliana Vásquez Ponce, Regina Aparecida Garcia Lima   +7 more
wiley   +1 more source

Epicoccin A Ameliorates PD-like Symptoms in Zebrafish: Enhancement of PINK1/Parkin-Dependent Mitophagy and Inhibition of Excessive Oxidative Stress

Marine Drugs
Parkinson’s disease (PD) is the second most prevalent neurodegenerative disorder, yet effective agents for its prevention and therapy remain highly limited.
Haicheng Ye, Dan Li, Lei Zhang, Yufei Wang, Cong Wang, Meng Jin, Houwen Lin, Peihai Li, Chen Sun, Ning Li   +9 more
doaj   +1 more source

The MC@NLO 4.0 Event Generator [PDF]

, 2010
This is the user's manual of MC@NLO 4.0. This package is a practical implementation, based upon the Fortran HERWIG and Herwig++ event generators, of the MC@NLO formalism, which allows one to incorporate NLO QCD matrix elements consistently into a parton ...
Frixione, Stefano, Stoeckli, Fabian, Torrielli, Paolo, Webber, Bryan R., White, Chris D.   +4 more
core   +1 more source

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

From theory to practice in training health researchers in patient and public involvement: a scoping review protocol

Systematic Reviews
Background Patient and public involvement (PPI) aims to increase the relevance and impact of research by ensuring that outcomes align with the real needs of those involved.
Caline Jesus, Isabelly Cristina Rodrigues Regalado, Karolinne Souza Monteiro, Adriana Gomes Magalhães, Paula Silva de Carvalho Chagas, Christina D. C. M. Faria, Vanessa Vega Córdova, Izaskun Álvarez-Aguado, Eve Namisango, Christopher Morris, Egmar Longo   +10 more
doaj   +1 more source

Comparison of genome-wide association methods in analyses of admixed populations with complex familial relationships. [PDF]

PLoS ONE, 2014
Population structure is known to cause false-positive detection in association studies. We compared the power, precision, and type-I error rates of various association models in analyses of a simulated dataset with structure at the population (admixture ...
Naveen K Kadri, Bernt Guldbrandtsen, Peter Sørensen, Goutam Sahana   +3 more
doaj   +1 more source

Pulmonary Dysfunction Is Associated With Sleep Study Abnormalities in Children With Sickle Cell Disease: A Multicenter Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pulmonary dysfunction and sleep abnormalities are common in children with sickle cell disease (SCD) and are associated with worse clinical outcomes. Whether spirometry abnormalities are associated with polysomnography (PSG) findings remains unclear.
Ammar Saadoon Alishlash, Anis Rabbani Nourani, A. K. M. Fazlur Rahman, Dima Ezmigna, Tarig Ali‐Dinar   +4 more
wiley   +1 more source

Inclusive and Enjoyable Physical Activity for Older Adults: The JOIN4JOY Project

Baltic Journal of Sport and Health Sciences
Purpose: Older adults remain the least physically active group in Europe, with barriers such as low socioeconomic status, health limitations, and social exclusion contributing to inactivity.
Erika Karkauskienė, Laura Coll-Planas, Andrea Fuente-Vidal, Javier Jerez-Roig, Montse Romero-Mas, Paolo Caserotti, Mathias Skjødt, Dhayana Dallmeier, Guillaume Lefebvre, Lucie Bassinah, Dolores Forgione, Ricard Castro-Prat, Eduard Minobes-Molina, Sergi Blancafort Alias, Blanca Roman-Viñas, José Luis Socorro-Cumplido, Ainhoa Nieto-Guisado, Oriol Sansano-Nadal, Maria Giné-Garriga   +18 more
doaj   +1 more source