Results 81 to 90 of about 5,612,897 (293)
Models and Frameworks: A Synergistic Association for Developing Component-Based Applications
The Scientific World Journal, 2014 The use of frameworks and components has been shown to be effective in improving software productivity and quality. However, the results in terms of reuse and standardization show a dearth of portability either of designs or of component-based ...
Diego Alonso +4 more
doaj +1 more source
Defining Roles in Pediatric Palliative Care: Perspectives From Oncology and Palliative Care Teams
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Early integration of pediatric palliative care (PPC) is associated with improved symptom management, quality of life, and healthcare utilization for children with cancer. Despite this, variation persists in how PPC is understood, operationalized, and integrated within pediatric oncology programs. In particular, ambiguity surrounding
Leeat Granek +13 more
wiley +1 more source
Region-Based Association Test for Familial Data under Functional Linear Models.
PLoS ONE, 2015 Region-based association analysis is a more powerful tool for gene mapping than testing of individual genetic variants, particularly for rare genetic variants.
Gulnara R Svishcheva +2 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Survivors of childhood acute lymphoblastic leukemia (ALL) often exhibit early deficits in muscle and movement competence, which can compromise long‐term health. Integrative neuromuscular training (INT), a multifaceted approach combining fundamental movement activities with strength exercises, may help address these deficits during ...
Anna Maria Markarian +7 more
wiley +1 more source
Context, cortex, and associations: a connectionist developmental approach to verbal analogies
Frontiers in Psychology, 2013 We present a PDP model of binary choice verbal analogy problems (A:B as C:[D1|D2], where D1 and D2 represent choice alternatives). We train a recurrent neural network in item-relation- item triples and use this network to test performance on analogy ...
Pavlos eKollias, James L McClelland
doaj +1 more source
Genetic association models are robust to common population kinship estimation biases. [PDF]
Genetics, 2023 Hou Z, Ochoa A.
europepmc +1 more source
Bayer AG v. Housey Pharmaceuticals: Protection for Biotechnological Research Tools under Section 271(g) Found Wanting [PDF]
, 2005 [Excerpt] Research tools, a subset of biotechnological inventions protected by process patents, are “tools that scientists use in the laboratory, including cell lines, monoclonal antibodies, reagents, animal models, growth factors, combinatorial ...
Barthalow, Matthew
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider +4 more
wiley +1 more source
Limitations of principal components in quantitative genetic association models for human studies. [PDF]
Elife, 2023 Yao Y, Ochoa A.
europepmc +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Treatment‐associated hepatotoxicity (TAH) is a common complication of pediatric acute lymphoblastic leukemia (ALL) treatment, but genetic risk factors remain poorly understood. We evaluated the SOD2 rs4880 variant in 544 children with ALL at Texas Children's Hospital. After adjusting for demographic and clinical covariates, the rs4880 C allele
Emily J. Mason +14 more
wiley +1 more source