Results 91 to 100 of about 1,960,778 (332)

Predictive energy landscapes for protein–protein association [PDF]

Proceedings of the National Academy of Sciences, 2012
We investigate protein–protein association using the associative-memory, water-mediated, structure, and energy model (AWSEM), a coarse-grained protein folding model that has been optimized using energy-landscape theory. The potential was originally parameterized by enforcing a funneled nature for a database of dimeric interfaces but was later further ...
Weihua, Zheng, Nicholas P, Schafer, Aram, Davtyan, Garegin A, Papoian, Peter G, Wolynes   +4 more
openaire   +2 more sources

Improved Outcomes for Older Children, Adolescents, and Young Adults With Neuroblastoma in the Post‐Immunotherapy Era: An Updated Report From the International Neuroblastoma Risk Group

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background We describe clinical and biologic characteristics of neuroblastoma in older children, adolescents, and young adults (OCAYA); describe survival outcomes in the post‐immunotherapy era; and identify if there is an age cut‐off that best discriminates outcomes.
Rebecca J. Deyell, Kavitha Srivatsa, Paola Angelini, Pei‐Chi Kao, Brady Payne, Arlene Naranjo, Sveva Castelli, Miho Kato, Miki Ohira, Ulriche Pöetschger, Yaël Mossé, Lucas Moreno, Meredith S. Irwin, Ramya Ramanujachar, Wendy B. London   +14 more
wiley   +1 more source

Prediction of Potential Small Molecule-Associated MicroRNAs Using Graphlet Interaction

Frontiers in Pharmacology, 2018
MicroRNAs (miRNAs) have been proved to be targeted by the small molecules recently, which made using small molecules to target miRNAs become a possible therapy for human diseases.
Na-Na Guan, Ya-Zhou Sun, Zhong Ming, Zhong Ming, Jian-Qiang Li, Xing Chen   +5 more
doaj   +1 more source

Classification [PDF]

, 2009
In Classification learning, an algorithm is presented with a set of classified examples or ‘‘instances’’ from which it is expected to infer a way of classifying unseen instances into one of several ‘‘classes’’.
Witten, Ian H.
core   +2 more sources

Review of: "Decoding the Correlation Coefficient: A Window into Association, Fit, and Prediction in Linear Bivariate Relationships" [PDF]

, 2023
Ikwuoche John David
openalex   +1 more source

Characterizing Parental Concerns About Lasting Impacts of Treatment in Children With B‐Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker, Sarah W. Alexander, Lisa M. Jacola, Kimberly A. Buff, Kyobin Hwang, Elham Hashemi, Gregory Stoddard, Lindsay A. Jibb   +7 more
wiley   +1 more source

PPDAMEGCN: Predicting piRNA‐Disease Associations Based on Multi‐Edge Type Graph Convolutional Network

IET Systems Biology
Recently, many studies have proven that Piwi‐interacting RNAs (piRNAs) play key roles in various biological processes and also associate with human complicated diseases.
Yinglong Peng, Shuang Chu, Xindi Huang, Yan Cheng   +3 more
doaj   +1 more source

NLO QCD corrections to hadronic Higgs production with heavy quarks

, 2003
The production of a Higgs boson in association with a pair of top-antitop or bottom-antibottom quarks plays a very important role at both the Tevatron and the Large Hadron Collider.
Balazs, Beenakker, Beenakker, Belyaev, Beneke, Bern, Bern, Bern, Boos, C.B. Jackson, Carena, D. Wackeroth, Dawson, Dawson, Dawson, Denner, Dicus, Dittmaier, Drollinger, Dürssen, Giele, Giele, Goldstein, Harlander, Harris, Keller, L. Reina, L.H. Orr, Lai, Maltoni, Maltoni, Passarino, Reina, Reina, S. Dawson, van Oldenborgh, Zeppenfeld, Zeppenfeld   +37 more
core   +2 more sources

Clinical Characteristics and Prognostic Risk Factors for Pediatric B‐Cell Lymphoblastic Lymphoma: A Multicenter Retrospective Cohort Study for China Net Childhood Lymphoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐cell lymphoblastic lymphoma (B‐LBL) represents a rare variety of non‐Hodgkin lymphoma, with limited research on its biology, progression, and management. Methods A retrospective analysis was performed on the clinical characteristics of 256 patients aged ≤18 years who received treatment under the China Net Childhood Lymphoma (CNCL)‐
Zhijuan Liu, Jian Wang, Ling Jin, Yanlong Duan, Fu Li, Yueping Jia, Leping Zhang, Xiaojun Yuan, Wei Liu, Ying Liu, Ansheng Liu, Mincui Zheng, Yunpeng Dai, Lian Jiang, Lirong Sun, Xiaowen Zhai, Rong Liu, Chunju Zhou, Zifen Gao, Yonghong Zhang, Xiaomei Yang   +20 more
wiley   +1 more source

Prediction of Potential miRNA–Disease Associations Through a Novel Unsupervised Deep Learning Framework with Variational Autoencoder

Cells, 2019
The important role of microRNAs (miRNAs) in the formation, development, diagnosis, and treatment of diseases has attracted much attention among researchers recently.
Li Zhang, Xing Chen, Jun Yin
doaj   +1 more source