Results 121 to 130 of about 1,960,778 (332)

Identification of cell subpopulations in each tumour type, their association with response to therapy, and prediction of effective alternative therapies

, 2022
Pavel Sumazin
openalex   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Ferritin level prospectively predicts hepatocarcinogenesis in patients with chronic hepatitis B virus infection [PDF]

, 2018
Previous studies have detected a higher level of ferritin in patients with hepatocellular carcinoma (HCC), but a potential causal association between serum ferritin level and hepatocarcinogenesis remains to be clarified.
Bian, Zhenyuan, Fang, Wan, Hann, Hie-Won, Tao, Kaishan, Wan, Shaogui, Wang, Chun, Wang, Yang, Ye, Zhong, Yin, Chun   +8 more
core   +1 more source

Predicting Contrast-Associated Acute Kidney Injury

JAMA Network Open
This systematic review and meta-analysis updates a previous evaluation of the performance of risk-prediction models for contrast-associated acute kidney injury.
Feng, Yunlin, Jun, Min, Wang, Amanda Y., Ren, Song, Weisbord, Steven D., Bellomo, Rinaldo, Ostermann, Marlies, Arnott, Clare, Gallagher, Martin   +8 more
openaire   +2 more sources

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Modeling the Risk of Team Sport Injuries: A Narrative Review of Different Statistical Approaches

Frontiers in Physiology, 2019
Injuries are a common occurrence in team sports and can have significant financial, physical and psychological consequences for athletes and their sporting organizations. As such, an abundance of research has attempted to identify factors associated with
Joshua D. Ruddy, Stuart J. Cormack, Rod Whiteley, Morgan D. Williams, Ryan G. Timmins, David A. Opar   +5 more
doaj   +1 more source

lncRNA-Disease Association Prediction Based On Weight Matrix And Projection Score [PDF]

, 2021
Bo Wang, Chao Zhang, Xiaoxin Du, Jianfei Zhang   +3 more
openalex   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Simple model for sequence prediction based on dendritic spatiotemporal integration

Sistemnì Doslìdženâ ta Informacìjnì Tehnologìï, 2018
Recent experiments on dendritic spatiotemporal integration reveal the much bigger computational potential of a single neuron. An individual dendritic branch can work as a coincidence detector due to a dendritic spike initiated with locally spatially and ...
Viacheslav M. Osaulenko
doaj   +1 more source