Results 191 to 200 of about 1,906,656 (324)

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

A lightweight single-view contrastive learning hypergraph neural network for food-microbe-disease association prediction. [PDF]

BMC Bioinformatics
Hu J, Hu M, Wu Y, Mu S, Huang D, Wang B, Gao Y, Gu S, Zhu J.   +8 more
europepmc   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Corrigendum: IDLDA: An Improved Diffusion Model for Predicting LncRNA–Disease Associations

Frontiers in Genetics, 2020
Qi Wang, Qi Wang, Guiying Yan, Guiying Yan   +3 more
doaj   +1 more source

Contrastive hypergraph collaborative filtering for transfer RNA-disease association prediction. [PDF]

Brief Bioinform
Ouyang T, Zhang Y, Huang Z, Deng L.
europepmc   +1 more source

Liver and Blood Expression Prediction Generated for Opportunities and challenges for transcriptome-wide association studies

, 2019
Michael Wainberg Alvaro Barbeira
openalex   +2 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Integrating multiple microRNA functional similarity networks for improved disease-microRNA association prediction. [PDF]

Biol Methods Protoc
Le DH.
europepmc   +1 more source

BNPMDA: Bipartite Network Projection for MiRNA–Disease Association prediction

Bioinform., 2018
Xing Chen, Di Xie, Lei Wang, Qi Zhao, Zhuhong You, Hongsheng Liu   +5 more
semanticscholar   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source