Results 71 to 80 of about 1,906,656 (324)

Sex differences in the association between plasma copeptin and incident type 2 diabetes: the Prevention of Renal and Vascular Endstage Disease (PREVEND) study [PDF]

, 2012
AIMS/HYPOTHESIS: Vasopressin plays a role in osmoregulation, glucose homeostasis and inflammation. Therefore, plasma copeptin, the stable C-terminal portion of the precursor of vasopressin, has strong potential as a biomarker for the cardiometabolic ...
A Abbasi, A Tanoue, A. Abbasi, AD Pradhan, AH Brantsma, B Balkau, B Buijsse, B Thorand, B Thorand, C Herder, CJ Kirk, D. Postmus, E Kajantie, E Meijer, E. Corpeleijn, E. Meijer, EL Ding, G. Navis, GS Collins, H. L. Hillege, HJ Lambers Heerspink, J Struck, J. Struck, JM Halimi, K McGeechan, K Nakamura, LD Simmler, ME Rhodes, MJ Pencina, NG Morgenthaler, NR Cook, NS Stachenfeld, R. O. B. Gans, R. P. Stolk, R. T. Gansevoort, RL Zerbe, S Enhorning, S Enhorning, S Oertelt-Prigione, S Oshikawa, S. J. L. Bakker, SS Bhandari, T Aoyagi, TB Monster, U Saleem, V Salomaa, W Fenske, Y Fujiwara   +47 more
core   +4 more sources

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Identification and Analysis of Human Microbe-Disease Associations by Matrix Decomposition and Label Propagation

Frontiers in Microbiology, 2019
Studies have shown that microbes exist widely in the human body and are closely related to human complex diseases. Predicting potential associations between microbes and diseases is conducive to understanding the mechanisms of complex diseases and can ...
Jia Qu, Yan Zhao, Jun Yin
doaj   +1 more source

Prediction of Metabolic Pathways Involvement in Prokaryotic UniProtKB Data by Association Rule Mining

, 2016
The widening gap between known proteins and their functions has encouraged the development of methods to automatically infer annotations. Automatic functional annotation of proteins is expected to meet the conflicting requirements of maximizing ...
Boudellioua, Imane, Hoehndorf, Robert, Martin, Maria, Saidi, Rabie, Solovyev, Victor   +4 more
core   +2 more sources

A working model for cytoplasmic assembly of H/ACA snoRNPs

FEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

Identifying and Exploiting Potential miRNA-Disease Associations With Neighborhood Regularized Logistic Matrix Factorization

Frontiers in Genetics, 2018
With the rapid development of biological research, microRNAs (miRNA) have become an attractive topic because lots of experimental studies have revealed the significant associations between miRNAs and diseases.
Bin-Sheng He, Jia Qu, Qi Zhao, Qi Zhao
doaj   +1 more source

XGBCDA: a multiple heterogeneous networks-based method for predicting circRNA-disease associations

BMC Medical Genomics, 2022
Background Biological experiments have demonstrated that circRNA plays an essential role in various biological processes and human diseases. However, it is time-consuming and costly to merely conduct biological experiments to detect the association ...
Siyuan Shen, Junyi Liu, Cheng Zhou, Yurong Qian, Lei Deng   +4 more
doaj   +1 more source

Track Segment Association Method Based on Bidirectional Track Prediction and Fuzzy Analysis

Aerospace, 2022
Due to sensor characteristics, geographical environment, electromagnetic interference, electromagnetic silence, information countermeasures, and other reasons, the phenomenon of track breakages occur in the process of aircraft track data processing.
Yupeng Cao, Jiangwei Cao, Zhiguo Zhou
doaj   +1 more source

Gene Function Prediction from Functional Association Networks Using Kernel Partial Least Squares Regression [PDF]

, 2015
With the growing availability of large-scale biological datasets, automated methods of extracting functionally meaningful information from this data are becoming increasingly important.
Bähler, J, Lees, J, Lehtinen, S, Orengo, C, Shawe-Taylor, J   +4 more
core   +1 more source

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

FEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker, Swantje Kebel, Lea Völkening, Anna Vatselia, Louisa Weinhold, Girmay Asgedom, Axel Schambach, Detlev Schindler, Thilo Dörk, Kristine Bousset   +9 more
wiley   +1 more source