Results 151 to 160 of about 9,278,183 (294)

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Texas Osteopathic Medical Association (TOMA) Archives

open access: yes, 2003
Finding aid for Texas Osteopathic Medical Association (TOMA) ArchivesThe Texas Osteopathic Medical Association was organized on November 29, 1900 in Sherman, Texas under the name Texas Association for the Advancement of Osteopathy. David L.
Texas Osteopathic Medical Association (TOMA)
core  

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Mining Text Classification Rules Based on Weighted Frequent Itemsets

open access: yes工程科学与技术, 2008
:The size of text and weight of elements in feature vectors may affect text classification rule. In order to improve the classification accuracy,new concepts of the weighted frequent items and a weighted frequent item set mining algorithm to highlight ...
doaj  

Exploring dietary behaviors among healthcare providers: based on association rule mining. [PDF]

open access: yesFront Public Health
Shu T   +7 more
europepmc   +1 more source

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