Results 71 to 80 of about 17,882 (265)

Applying negative rule mining to improve genome annotation

open access: yesBMC Bioinformatics, 2007
Background Unsupervised annotation of proteins by software pipelines suffers from very high error rates. Spurious functional assignments are usually caused by unwarranted homology-based transfer of information from existing database entries to the new ...
Frishman Goar   +2 more
doaj   +1 more source

Bioinspired Microreactor for Iodide Adsorption and Photooxidation Recovery

open access: yesAdvanced Science, EarlyView.
A bioinspired micro‐ionic‐reactor based on porous organic polymer (MIR‐POP) integrates rapid iodide capture with in situ photooxidative conversion, achieving record uptake capacity and high uptake efficiencies in simulated mining wastewater and natural brine. This bioinspired microreactor strategy offers a new avenue for sustainable iodine recovery and
Xuewen Cao   +8 more
wiley   +1 more source

Liver Stiffness Rises Early in MASLD and Drives Inflammation, Lipid Dysmetabolism, and Fibrosis via Piezo1–YAP Mechanotransduction

open access: yesAdvanced Science, EarlyView.
Progressive stiffening of the hepatic extracellular matrix and free fatty acid overload activate the mechanosensor Piezo1 in steatotic hepatocytes, inducing calcium influx and nuclear translocation of Yes‐associated protein. YAP‐dependent nuclear signaling further drives inflammatory and fibrotic gene programs, lipid metabolic reprogramming, and ...
Juan Ma   +15 more
wiley   +1 more source

Xanthatin Targets CISD1 to Drive Ferroptosis and Mitophagy as a Dual Anticancer Strategy in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
Triple‐negative breast cancer has a poor prognosis. Xanthatin directly targets and degrades CISD1, triggering ferroptosis through iron dysregulation. The concurrently activated mitophagy synergistically amplifies ferroptotic cell death. Xanthatin also demonstrates potent in vivo anti‐tumor efficacy with minimal toxicity, highlighting its therapeutic ...
Qinwen Liu   +9 more
wiley   +1 more source

A Multi-Objective Nutcracker Optimization Algorithm Based on Cubic Chaotic Map for Numerical Association Rule Mining

open access: yesApplied Sciences
Traditional numerical association rule mining optimization algorithms have limitations in handling discrete attributes, and they are susceptible to becoming trapped in local optima, uneven population distribution, and poor convergence.
Qiwei Hu, Shengbo Hu, Mengxia Liu
doaj   +1 more source

Selective Lithium Recovery via Photothermal Evaporation and Hydration‐Controlled Adsorption

open access: yesAdvanced Science, EarlyView.
A bilayer Mo‐LDH@Sponge composite is developed to couple interfacial photothermal evaporation with hydration‐controlled lithium adsorption. Solar‐induced heating dynamically regulates Li+ hydration and transport, enabling selective lithium capture from saline water. This work provides mechanistic insight into photothermal–adsorption coupling for energy‐
Yanan Pan   +4 more
wiley   +1 more source

MicrobeDiscover: A Knowledge Graph–Enabled AI Framework for Identifying Microbes for Inorganic Nanomaterial Biosynthesis

open access: yesAdvanced Science, EarlyView.
Microbial synthesis of nanomaterials (NMs) is eco‐friendly, but the screening of microorganisms is limited by inefficient traditional methods (currently only involving∽400 microorganisms/90 NMs). We propose AI framework MicrobeDiscover, integrating a knowledge graph of microbe‐NM interactions.
Ludi Wang   +12 more
wiley   +1 more source

Enhancing Retail Strategies Through Anomaly Detection in Association Rule Mining

open access: yesIEEE Access
Association rule mining (ARM) is a fundamental technique for uncovering meaningful patterns and relationships within retail datasets, providing valuable insights for decision-making processes in the retail industry.
Bijayini Mohanty   +2 more
doaj   +1 more source

Mining Triadic Association Rules

open access: yesComputer Science & Information Technology ( CS & IT ), 2013
The objective of this research is to extract triadic association rules from a triadic formal context K := (K 1, K 2, K 3, Y) where K 1, K 2 and K 3 respectively represent the sets of objects, properties (or attributes) and conditions while Y is a ternary relation between these sets.
Sid Ali Selmane   +3 more
openaire   +1 more source

Integrating Spatial Proteogenomics in Cancer Research

open access: yesAdvanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang   +13 more
wiley   +1 more source

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