Results 121 to 130 of about 2,309,085 (285)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Detection of Subarachnoid Hemorrhage in Computed Tomography Using Association Rules Mining. [PDF]

Comput Intell Neurosci, 2022
Alwageed HS.
europepmc   +1 more source

arules - A Computational Environment for Mining Association Rules and Frequent Item Sets [PDF]

Mining frequent itemsets and association rules is a popular and well researched approach for discovering interesting relationships between variables in large databases.
Bettina Grün, Kurt Hornik, Michael Hahsler   +2 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Integrated Bayesian and association-rules methods for autonomously orienting COVID-19 patients. [PDF]

Med Biol Eng Comput, 2022
Thaljaoui A, Khediri SE, Benmohamed E, Alabdulatif A, Alourani A.   +4 more
europepmc   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Retracted: An Evaluation Model for the Influence Factors of Interest in Literature Courses Based on Data Analysis and Association Rules in a Small-Sample Environment. [PDF]

J Environ Public Health, 2023
Environmental And Public Health JO.
europepmc   +1 more source

Post-processing of association rules. [PDF]

In this paper, we situate and motivate the need for a post-processing phase to the association rule mining algorithm when plugged into the knowledge discovery in databases process.
Baesens, Bart, Vanthienen, Jan, Viaene, Stijn   +2 more
core  

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Identification of Key Contributing Factors and Risk Propagation Paths in Safety Accidents at Chinese Chemical Enterprises

Safety
To address the complex and uncertain causes of safety accidents in chemical enterprises, this study applied text mining techniques to systematically extract 29 causative factors from 422 accident reports.
Zhiheng Ni, Zhen Li, Mingyu Zhang, Otsile Morake   +3 more
doaj   +1 more source