Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Hiding Predictive Association Rules on Horizontally Distributed Data
[[abstract]]Hiding Predictive Association Rules on Horizontally Distributed ...
王學亮
core
Mining association rules between lichens and air quality to support urban air quality monitoring in Nigeria. [PDF]
Lawal O, Ogugbue CJ, Imam TS.
europepmc +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Efficient Hiding of Collaborative Recommendation Association Rules with Updates
[[abstract]]Efficient Hiding of Collaborative Recommendation Association Rules with ...
王學亮
core
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Analysis of multiple chronic disease characteristics in middle-aged and elderly South Koreans by exercise habits based on association rules mining algorithm. [PDF]
Huang Y, Su Y, Byun Y, Lee Y, Kim S.
europepmc +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Hiding Constrained Association Rules in Privacy Preserving Data Mining
[[abstract]]Overview of Hiding Constrained Association Rules in Privacy Preserving Data ...
王學亮
core
Data Mining and Meta-Analysis of Psoriasis Based on Association Rules. [PDF]
Ou J, Zhang J.
europepmc +1 more source

