Results 111 to 120 of about 443 (241)
The hippocampal formation and action at a distance. [PDF]
Proc Natl Acad Sci U S A, 2021 Nadel L.
europepmc +1 more source
Associationer till färgat ljus
, 2020 Genom belysning kan man effektivt förmedla budskap eller känslor, speciellt med hjälp av färger. Färgat ljus används idag för att bland annat markera högtider och temadagar och profilera varumärken. Det är dock inte självklart vilka känslor eller budskap färgat ljus faktiskt förmedlar, då forskningen i ämnet är begränsad. Syftet med den här studien var
Ikenstein, Vincent, Takkunen, Markku
openaire +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Tracking the digital health gap in elderly: A study in Italian remote areas. [PDF]
Health Policy, 2023 Vainieri M +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Mapping obesity and diabetes' representation on Twitter: the case of Italy. [PDF]
Front Sociol, 2023 Lenzi FR, Iazzetta F.
europepmc +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source