Results 61 to 70 of about 443 (241)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Educação em RevistaRESUMO: O artigo se propõe a discutir as práticas e as expressões de sociabilidade dos negros na Província de Pernambuco na primeira metade do século XIX, entendendo-as enquanto instâncias educativas criadas pela população negra.
Itacir Marques da Luz
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Cuadernos de Historia de EspañaLa consideración del asociacionismo como un marco de referencia y expresión, no tan sólo del sentir religioso y de actitudes benéficas sino también como instancia de prácticas sociales vinculadas a la esfera de lo prescripto por los poderes públicos ...
Mariana A. Fábrega
doaj
Utilitarianism: a psychophysical perspective
Paidéia (Ribeirão Preto), 2004 The psychological doctrines of empiricism, associationism, and hedonism served as intellectual sources for the development of utilitarianism in the 18th century and psychophysics in the 19th.
Lawrence Marks
doaj +1 more source
Associations do not energize behavior: on the forgotten legacy of Kurt Lewin. [PDF]
Psychol Res, 2022 Eder AB, Dignath D.
europepmc +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
piano bAnalyzing the Italian feminist movement of the early 20th century, the historical phenomenon that stands out is that of women's associationism. Studying the aggregation of women's groups allows us to trace a biography of the movement and contributes to ...
Emanuele Carlenzi, Martina Cavalli
doaj +1 more source