Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
AGENTS OF TRUST: BUSINESS ASSOCIATIONS IN AGRI-FOOD SUPPLY SYSTEMS [PDF]
The generation of trust between business partners is a strategic issue for firms in competitive agri-food markets. It is asserted that business associations can be important facilitators of trust between firms.
Rademakers, Martijn F.L.
core
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Political Participation of Ethnic Associations: Exploring the Importance of Organisational Level Differences in Resources, Motivation and Recruitment Networks [PDF]
In this paper, we apply the Civic Voluntarism Model (CVM) proposed by Verba, Schlozman and Brady on the organisational level. Simultaneously contributing to the research on the political integration of ethnic minorities, we examine resources, motivation ...
Bengtsson, Bo, Strömblad, Per
core
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Glasgow and West of Scotland Forum of Housing Associations' Response to the Scottish Government's Regeneration Discussion Document : Building a Sustainable Future [PDF]
First paragraph: Earlier this year, the Scottish Government published a regeneration discussion document, Building a Sustainable Future, to encourage debate about how to deliver regeneration in difficult economic times.
McKee, Kim, McKee, Kim; id_orcid
core
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Industrial Associations as a Channel of Business-Government Interactions in an Imperfect Institutional Environment: The Russian Case [PDF]
International lessons from emerging economies suggest that business associations may provide an effective channel of communication between the government and the private sector.
A. Yakovlev, A. Govorun
core
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Meaningful youth engagement in sexual and reproductive health and rights decision making
Klaudia Szymuś +7 more
doaj +1 more source

