Results 141 to 150 of about 3,038,389 (258)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Minutes of Meeting: Management of Library Associations Section, Monday, 13 January, 2025

The first MLAS Standing Committee Members Meeting for the year 2025 was held on 13 January 2025 via Zoom. MLAS held an IFLA Elections 2025 Orientation for MLAS Members. before the MLAS SC meeting. The orientation was chaired by Loida, MLAS Chair and Ms.
IFLA Management of Library Associations Section
core  

Longitudinal Repeated Protein Measurements in a Multiethnic Cohort Identify Novel Diabetes Biomarkers That Reveal Unique Disease Pathways. [PDF]

Diabetes
Chen ZZ, Mi MY, Barber J, Tiwari G, Adams CD, Deng S, Shin CY, Farrell L, Rao P, Cruz DE, Wilson JG, Sevilla-Gonzalez M, Chen YI, Guo X, Goodarzi MO, Taylor KD, Tahir UA, Rich SS, Wood AC, Gerszten RE, Rotter JI.   +20 more
europepmc   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Associations between air pollution and pediatric asthma hospitalizations across vulnerable groups in Louisiana. [PDF]

Environ Epidemiol
Luglio DG, Hossain CA, Monis RP, Ramesh B, Proven E, Rahman MM.   +5 more
europepmc   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Continuous Glucose Monitoring Metrics and Risks of Severe Hypoglycemia and Diabetic Ketoacidosis in Type 1 Diabetes: A Pooled Analysis. [PDF]

Diabetes Care
He JH, Malek ND, Zeger SL, Echouffo-Tcheugui JB, Fang M, Selvin E.   +5 more
europepmc   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

COLLECTIVE ACTION AND INFORMAL FINANCIAL INSTITUTIONS: AN EMPIRICAL ANALYSIS OF ROTATING AND SAVINGS CREDIT ASSOCIATIONS (ROSCAS) IN SENEGAL [PDF]

This study analyzes how rotating savings and credit associations (ROSCAs) in Senegal were able to overcome the collective action dilemma, maintain institutional performance, and remain sustainable over time. This study models cooperation among members as
Fadiga-Stewart, Leslie A., Fadiga, Mohamadou L.   +1 more
core  

Longitudinal Associations Among Workplace Social Capital, Career Calling and Work Engagement Among Nurses: A Three-Wave Cross-Lagged Panel Study. [PDF]

Healthcare (Basel)
Sun N, Liang Y, Ni Y, Zhang R, Xing Y, Bie F, Song D, Cai L.   +7 more
europepmc   +1 more source