Results 151 to 160 of about 3,038,389 (258)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Meta-analysis of over 8,000 individuals from Hawai'i and Samoa for genetic associations to cardiometabolic phenotypes. [PDF]

PLoS Genet
Dinh BL, Wang X, Sheng X, Wan P, Srivastava AK, Naseri T, Viali S, Samoan Obesity, Lifestyle and Genetic Adaptations (OLaGA) Study Group, Wilkens LR, Le Marchand L, Haiman CA, Weeks DE, Chiang CWK, Carlson JC.   +14 more
europepmc   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Code déontologique de l\u27ECIA [PDF]

Élaboré dans le cadre des travaux de l’European Council of Information Associations (ECIA), le code de déontologie des professionnels de l’Information et Documentation présenté ici est commun à tous les membres de la profession, dans quelque pays de l ...
European Council of Information Associations (ECIA)
core  

Minutes of Meeting: Management of Library Associations Section, 05 March 2024

Loida Garcia Febo, MLAS Chair welcome all MLAS Standing Committee and NPSIG Convenor to the meeting. Among the matters discussed at the meeting include the following: Report from the IFLA Governing Board; IFLA Information Futures Summit; IFLA Advisory ...
IFLA Management of Library Associations Section Standing Committee
core   +1 more source

Associations of Ambient Air Pollution and Road-Related Environmental Characteristics with Cardiometabolic Health: The Role of Walking. [PDF]

Toxics
Cerin E, Alvarado-Molina M, Akram M, Chan YK, Shaw JE, Knibbs LD, Barnett A.   +6 more
europepmc   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Prospective associations of childhood metal mixtures with metabolic health in a Mexico City cohort. [PDF]

Environ Epidemiol
Gigot C, Tung PW, Wu H, Estrada-Gutierrez G, Tolentino MC, Cantoral A, Landero J, Wright RO, Tellez-Rojo MM, Kupsco A.   +9 more
europepmc   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Diet and physical activity in multiple sclerosis: associations with quality of life and disability by disease duration. [PDF]

Neurol Sci
Nag N, Yu M, Román CAF, Vaglio-Garro A, Schmidt H.   +4 more
europepmc   +1 more source