Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Erratum: The Decline of the Canadian Sociology and Anthropology Association
, 2003 openalex +1 more source
Review of: "The Association Between Fibromyalgia, Hypermobility and Neurodivergence Extends to Families: Brief Report" [PDF]
, 2023 Peter Woodruff
openalex +1 more source
Trade Associations: Competition Law Advocates or Offenders?
, 2016 For centuries, trade associations throughout the world have played a critical role representing businesses, providing services such as lobbying governments, conducting research and providing various forms of assistance to their members.
Burgess, Rachel
core
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Final report of the Task Force on Law Library Associations
, 2007 Title from PDF caption, p. [3] (viewed on May 21, 2007).; "March 26, 2007"--P. [1]
Ohio. General Assembly. Task Force on Law Library Associations. +1 more
core
Exploring causal correlations between oily fish intake and multiple sclerosis: A two-sample Mendelian randomization study. [PDF]
Asia Pac J Clin NutrChang S, Shi K, Zhang M.
europepmc +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
The Emergence of Trade Associations as Agents of Environmental Performance Improvement
, 2002 This paper explores a surprising phenomenon: the emergence of trade associations as agents of environmental performance improvement. Trade associations in the United States have historically fought environmental regulation, not embraced it.
Nash, Jennifer
core