Results 201 to 210 of about 3,623,763 (357)

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Research interventions to strengthen irrigators' associations

open access: yes
Irrigation management, Water distribution, Financing, Data collection, Operations, Maintenance, Performance indexes, Privatization, Farmer-agency interactions, Institution building, Farmers associations, Training, Participatory management, Leadership ...
Sala, Antonio Lea R.   +2 more
core  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Political Participation of Ethnic Associations: Exploring the Importance of Organisational Level Differences in Resources, Motivation and Recruitment Networks [PDF]

open access: yes
In this paper, we apply the Civic Voluntarism Model (CVM) proposed by Verba, Schlozman and Brady on the organisational level. Simultaneously contributing to the research on the political integration of ethnic minorities, we examine resources, motivation ...
Bengtsson, Bo, Strömblad, Per
core  

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Genomics-informed approach identifies which cell types regulate the metabolome. [PDF]

open access: yesBioinformatics
Krupkin H   +5 more
europepmc   +1 more source

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