Results 211 to 220 of about 3,623,763 (357)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

COLLECTIVE ACTION AND INFORMAL FINANCIAL INSTITUTIONS: AN EMPIRICAL ANALYSIS OF ROTATING AND SAVINGS CREDIT ASSOCIATIONS (ROSCAS) IN SENEGAL

open access: yes
This study analyzes how rotating savings and credit associations (ROSCAs) in Senegal were able to overcome the collective action dilemma, maintain institutional performance, and remain sustainable over time. This study models cooperation among members as
Fadiga-Stewart, Leslie A.   +1 more
core  

Genetic-epigenetic interactions (meQTLs) in orofacial clefts etiology. [PDF]

open access: yesMol Genet Genomics
Petrin AL   +12 more
europepmc   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Exploring the complexities of vaccine sentiment among healthcare and public health professionals: essential strategies for encouraging vaccine uptake

open access: yesFrontiers in Public Health
Mariana Gonzalez Utrilla   +6 more
doaj   +1 more source

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