Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
(σ,τ )– (J,R) – DERIVATIONS ON JORDAN IDEALS
Let R be an associative ring with center Z(R). A well known results proved by Bell and kappe concering derivations in prime rings have been extensively studied by many authors, several of these outhers extended these result for a - derivation like ...
Ikram A. Saed
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Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Tricrilactones A–H, Potent Antiosteoporosis Macrolides with Distinctive Ring Skeletons from Trichocladium crispatum, an Alpine Moss‐Associated Fungus [PDF]
Wenbo Han +8 more
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Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Representation rings of extensions of Hopf algebra of Kac-Paljutkin type
In this paper, we focus on studying two classes of finite dimensional $ \Delta $-associative algebras, which are extensions of a family of $ 2n^2 $-dimensional Kac-Paljutkin type semi-simple Hopf algebras $ H_{2n^2} $.
Dong Su, Shilin Yang
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On the ideals and automorphisms of non-associative rings [PDF]
M. F. Smiley
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EPH119 Patient Characteristics, Outcomes, and Hospital Resource Utilization Associated with Surgical Mitral Ring Annuloplasty [PDF]
Godfred Marfo +2 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Algebraic Properties of Semi-Direct Sums of Rings
Let R be an associative ring not necessarily with unity. We say that R is a semi-direct sum of rings S and I, if R = S + I, where S is a subring of a ring R, I is an ideal of R and S ∩ I = {0}.
Nowakowska Marta
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