Results 41 to 50 of about 302,048 (293)

Monitoring and Load Forecasting of IP Telephony Server in Digital Educational Ecosystems

Кібернетика та комп'ютерні технології
Introduction. The article addresses the relevant scientific and practical problem of developing and substantiating a subsystem for intelligent server monitoring and load forecasting in IP telephony networks.
Andrii Khyzhniak, Artem Mylytsia, Pavlo Byvoino, Oleksandr Zavorotnyi   +3 more
doaj   +1 more source

A Bibliography of Torres Strait Education

The Australian Journal of Indigenous Education, 2003
This non-selective bibliography is limited to published material and is part of the Bibliography of Torres Strait to be found on the Aboriginal andTorres Strait Islander Studies Unit’s website at .
Anna Shnukal
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

MANIPULATION OF SPATIAL FIELD DISTRIBUTION IN A PLANAR MICROWAVE PHOTON-MAGNON CONVERTER [PDF]

Radio Physics and Radio Astronomy
Subject and Purpose. The research addresses planar photon-magnon (P-M) converters that efficiently convert between microwave photons and magnons and are essential components in emerging quantum technologies.
S. Yu. Polevoy, T. Bozkurt, B. Rami, S. I. Tarapov   +3 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

AStERISK: Auction-based Shared Economy ResolutIon Markets for Blockchain Platforms

Proceedings 2019 Workshop on Decentralized IoT Systems and Security, 2019
—Recent developments in blockchains and edge computing allow deployment of decentralized shared economy platforms with utility token support, where tokens (in the form of altcoins) secure and reward useful work. However, the majority of the systems being
A. Sonnino, M. Król, Argyrios G. Tasiopoulos, I. Psaras   +3 more
semanticscholar   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Discourse of Non-Heteronormative Labelling in German-Language Press: The Case of Gendersternchen

Slovenščina 2.0: Empirične, aplikativne in interdisciplinarne raziskave, 2019
The Gendersternchen (*), German for Gender Star or Gender Asterisk, is one of the means available in the Germans language for referring to non-heteronormative persons. The aim of the present article is to analyse this discourse, i.e.
Vít Kolek
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source