Results 141 to 150 of about 3,577 (174)
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Asthenozoospermia and the human sperm mid-piece

Human Reproduction, 1995
This study provides a quantitative comparison between surface and ultrastructural features of motile spermatozoa in asthenozoospermic and fertile men. The study group consisted of 10 individuals with persistent asthenozoospermia and the controls were 10 fertile donors to a sperm bank.
A J, Mundy, T A, Ryder, D K, Edmonds
openaire   +2 more sources

ADGB variants cause asthenozoospermia and male infertility

Human Genetics, 2023
Asthenozoospermia is one of the main factors leading to male infertility, but the genetic mechanisms have not been fully elucidated. Variants in the androglobin (ADGB) gene were identified in an infertile male characterized by asthenozoospermia. The variants disrupted the binding of ADGB to calmodulin.
Ronggui Qu   +16 more
openaire   +2 more sources

Human Spermatozoal Nuclear Maturity in Normozoospermia and Asthenozoospermia

Archives of Andrology, 1988
Ejaculated human spermatozoa were studied to assess their nuclear maturity. After SDS or SDS-EDTA treatment, asthenozoospermic semen had a lower resistance to decondensation than normozoospermic semen and contained more stained immature nuclei after aniline blue staining. It showed a higher uptake of ethidium bromide, specific for DNA.
D, Colleu   +3 more
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In Vivo Therapies for Asthenozoospermia

1999
Motility is one of the major sperm characteristics needed to achieve a pregnancy in vivo. Several factors can affect sperm motility, some of which are relatively well known, such as ultrastructural tail defects (see previous chapters in this book).
openaire   +1 more source

Septins as Diagnostic Markers for a Subset of Human Asthenozoospermia

Journal of Urology, 2008
Septins are the major constituents of the annulus, a submembranous ring that separates the middle and principal pieces of spermatozoa. We previously reported its essential role in spermiogenesis and reproduction in mice. In the current study we investigated septin abnormality in infertile men.Semen samples from 108 infertile patients and 21 healthy ...
Yoshio, Sugino   +6 more
openaire   +2 more sources

MicroRNA profiling in spermatozoa of men with unexplained asthenozoospermia

Andrologia, 2019
Asthenozoospermia (AZS) which is characterised by decreased sperm motility is one of the main causes of male infertility. Recent studies demonstrated altered microRNAs (miRNAs) in total semen, seminal plasma and spermatozoa of asthenozoospermic men.
Zohreh Heidary   +3 more
openaire   +2 more sources

SEMG1 may be the candidate gene for idiopathic asthenozoospermia

Andrologia, 2013
Asthenozoospermia (AZS) is a major cause of male infertility, aetiology of which is reported to be related with gene mutation or deletion. However, studies on candidate genes for AZS are very scarce. In this study, we examined the gene expression profiles of asthenozoosperm. Gene expression profile analyses with microarray on spermatozoa specimens from
Q, Yu   +5 more
openaire   +2 more sources

L- carnitine in idiopathic asthenozoospermia: a multicenter study

Andrologia, 2009
The aim of the study described here was to evaluate any possible effect of L-carnitine on spermatozoal motility in a group of patients with unexplained asthenozoospermia in four different infertility centres. One hundred patients received 3 g d-1 of oral L-carnitine for 4 months.
Costa M.   +4 more
openaire   +2 more sources

Teratozoospermia and asthenozoospermia are associated with specific epigenetic signatures

Andrology, 2016
Semen analysis is commonly used as a tool to assess the fertility potential of a male, despite its relatively low predictive power. In this study, we have assessed associations between semen analysis findings (low count, low motility, low viability, poor sperm penetration assay results, poor morphology, and increased DNA damage) and DNA methylation ...
T G, Jenkins   +5 more
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Sperm metabolomic profiles of varicocele-associated asthenozoospermia

Journal of Pharmaceutical and Biomedical Analysis
Varicocele is a leading cause of male infertility, with asthenozoospermia being a common phenotype. The metabolic basis of varicocele-induced asthenozoospermia remains poorly understood, necessitating a comprehensive metabolic profiling study. This GC-MS-based metabolomic study investigated sperm metabolic profiles across three cohorts: healthy ...
Yuyang, Hou   +5 more
openaire   +2 more sources

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