Results 141 to 150 of about 3,577 (174)
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Asthenozoospermia and the human sperm mid-piece
Human Reproduction, 1995This study provides a quantitative comparison between surface and ultrastructural features of motile spermatozoa in asthenozoospermic and fertile men. The study group consisted of 10 individuals with persistent asthenozoospermia and the controls were 10 fertile donors to a sperm bank.
A J, Mundy, T A, Ryder, D K, Edmonds
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ADGB variants cause asthenozoospermia and male infertility
Human Genetics, 2023Asthenozoospermia is one of the main factors leading to male infertility, but the genetic mechanisms have not been fully elucidated. Variants in the androglobin (ADGB) gene were identified in an infertile male characterized by asthenozoospermia. The variants disrupted the binding of ADGB to calmodulin.
Ronggui Qu +16 more
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Human Spermatozoal Nuclear Maturity in Normozoospermia and Asthenozoospermia
Archives of Andrology, 1988Ejaculated human spermatozoa were studied to assess their nuclear maturity. After SDS or SDS-EDTA treatment, asthenozoospermic semen had a lower resistance to decondensation than normozoospermic semen and contained more stained immature nuclei after aniline blue staining. It showed a higher uptake of ethidium bromide, specific for DNA.
D, Colleu +3 more
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In Vivo Therapies for Asthenozoospermia
1999Motility is one of the major sperm characteristics needed to achieve a pregnancy in vivo. Several factors can affect sperm motility, some of which are relatively well known, such as ultrastructural tail defects (see previous chapters in this book).
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Septins as Diagnostic Markers for a Subset of Human Asthenozoospermia
Journal of Urology, 2008Septins are the major constituents of the annulus, a submembranous ring that separates the middle and principal pieces of spermatozoa. We previously reported its essential role in spermiogenesis and reproduction in mice. In the current study we investigated septin abnormality in infertile men.Semen samples from 108 infertile patients and 21 healthy ...
Yoshio, Sugino +6 more
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MicroRNA profiling in spermatozoa of men with unexplained asthenozoospermia
Andrologia, 2019Asthenozoospermia (AZS) which is characterised by decreased sperm motility is one of the main causes of male infertility. Recent studies demonstrated altered microRNAs (miRNAs) in total semen, seminal plasma and spermatozoa of asthenozoospermic men.
Zohreh Heidary +3 more
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SEMG1 may be the candidate gene for idiopathic asthenozoospermia
Andrologia, 2013Asthenozoospermia (AZS) is a major cause of male infertility, aetiology of which is reported to be related with gene mutation or deletion. However, studies on candidate genes for AZS are very scarce. In this study, we examined the gene expression profiles of asthenozoosperm. Gene expression profile analyses with microarray on spermatozoa specimens from
Q, Yu +5 more
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L- carnitine in idiopathic asthenozoospermia: a multicenter study
Andrologia, 2009The aim of the study described here was to evaluate any possible effect of L-carnitine on spermatozoal motility in a group of patients with unexplained asthenozoospermia in four different infertility centres. One hundred patients received 3 g d-1 of oral L-carnitine for 4 months.
Costa M. +4 more
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Teratozoospermia and asthenozoospermia are associated with specific epigenetic signatures
Andrology, 2016Semen analysis is commonly used as a tool to assess the fertility potential of a male, despite its relatively low predictive power. In this study, we have assessed associations between semen analysis findings (low count, low motility, low viability, poor sperm penetration assay results, poor morphology, and increased DNA damage) and DNA methylation ...
T G, Jenkins +5 more
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Sperm metabolomic profiles of varicocele-associated asthenozoospermia
Journal of Pharmaceutical and Biomedical AnalysisVaricocele is a leading cause of male infertility, with asthenozoospermia being a common phenotype. The metabolic basis of varicocele-induced asthenozoospermia remains poorly understood, necessitating a comprehensive metabolic profiling study. This GC-MS-based metabolomic study investigated sperm metabolic profiles across three cohorts: healthy ...
Yuyang, Hou +5 more
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